Evidence map›Paper›PMID 38793273›Full record

ArticleMaterials (Basel, Switzerland)2024

In Vitro Study of the Proliferation of MG63 Cells Cultured on Five Different Titanium Surfaces.

Roberto Campagna, Valentina Schiavoni, Enrico Marchetti, Eleonora Salvolini, Andrea Frontini, Francesco Sampalmieri, Fabrizio Bambini, Lucia Meme'

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Roberto CampagnaDepartment of Clinical Sciences, Polytechnic University of Marche, 60121 Ancona, Italy.ORCID 0000-0003-2607-2734
Valentina SchiavoniDepartment of Clinical Sciences, Polytechnic University of Marche, 60121 Ancona, Italy.
Enrico MarchettiDepartment of Life, Health, Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0001-6461-7876
Eleonora SalvoliniDepartment of Clinical Sciences, Polytechnic University of Marche, 60121 Ancona, Italy.ORCID 0000-0003-2405-8947
Andrea FrontiniDepartment of Life and Environmental Sciences, Polytechnic University of Marche, 60121 Ancona, Italy.ORCID 0000-0002-7381-4107
Francesco SampalmieriDepartment of Clinical Sciences, Polytechnic University of Marche, 60121 Ancona, Italy.
Fabrizio BambiniDepartment of Clinical Sciences, Polytechnic University of Marche, 60121 Ancona, Italy.ORCID 0000-0003-4371-900X
Lucia Meme'Department of Clinical Sciences, Polytechnic University of Marche, 60121 Ancona, Italy.ORCID 0000-0002-0441-3596

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of dental implants for prosthetic rehabilitation in dentistry is based on the concept of osteointegration. This concept enables the clinical stability of the implants and a total absence of inflammatory tissue between the implant surface and the bone tissue. For this reason, it is essential to understand the role of the titanium surface in promoting and maintaining or not maintaining contact between the bone matrix and the surface of the titanium implant. MATERIALS AND

methodsFive types of titanium discs placed in contact with osteoblast cultures of osteosarcomas were studied. The materials had different roughness. Scanning electron microscopy (SEM) photos were taken before the in vitro culture to analyze the surfaces, and at the end of the culturing time, the different gene expressions of a broad pattern of proteins were evaluated to analyze the osteoblast response, as indicated in the scientific literature.

resultsIt was demonstrated that the responses of the osteoblasts were different in the five cultures in contact with the five titanium discs with different surfaces; in particular, the response in the production of some proteins was statistically significant. DISCUSSION: The key role of titanium surfaces underlines how it is still possible to carry out increasingly accurate and targeted studies in the search for new surfaces capable of stimulating a better osteoblastic response and the long-term maintenance of osteointegration.

Indexed as

implant surfaceMG63osteointegrationsurface characteristics

Identifiers

PMID38793273
PMCPMC11122938

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.