Evidence map›Paper›PMID 38793192›Full record

ArticleMicromachines2024

Capillary Force-Driven Quantitative Plasma Separation Method for Application of Whole Blood Detection Microfluidic Chip.

Xiaohua Fang, Cuimin Sun, Peng Dai, Zhaokun Xian, Wenyun Su, Chaowen Zheng, Dong Xing, Xiaotian Xu, Hui You

Abstract read
In one paragraph

Article in Micromachines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaohua FangSchool of Mechanical Engineering, Guangxi University, Nanning 530004, China.
Cuimin SunSchool of Mechanical Engineering, Guangxi University, Nanning 530004, China.ORCID 0000-0003-4174-1094
Peng DaiSchool of Mechanical Engineering, Guangxi University, Nanning 530004, China.
Zhaokun XianSchool of Mechanical Engineering, Guangxi University, Nanning 530004, China.
Wenyun SuSchool of Mechanical Engineering, Guangxi University, Nanning 530004, China.
Chaowen ZhengSchool of Mechanical Engineering, Guangxi University, Nanning 530004, China.
Dong XingSchool of Mechanical Engineering, Guangxi University, Nanning 530004, China.
Xiaotian XuSchool of Mechanical Engineering, Guangxi University, Nanning 530004, China.
Hui YouSchool of Mechanical Engineering, Guangxi University, Nanning 530004, China.ORCID 0000-0002-6821-6188

Funding

Guangxi Bagui Scholars Project No.2019A02Guangxi University Innovation and Development Doubling Plan Project No.202201343&No.202201369the National Natural Science Foundation of China Grant No. 62304057
6 · The paper itself

Abstract

Separating plasma or serum from blood is essential for precise testing. However, extracting precise plasma quantities outside the laboratory poses challenges. A recent study has introduced a capillary force-driven membrane filtration technique to accurately separate small plasma volumes. This method efficiently isolates 100-200 μL of pure human whole blood with a 48% hematocrit, resulting in 5-30 μL of plasma with less than a 10% margin of error. The entire process is completed within 20 min, offering a simple and cost-effective approach to blood separation. This study has successfully addressed the bottleneck in self-service POCT, ensuring testing accuracy. This innovative method shows promise for clinical diagnostics and point-of-care testing.

Indexed as

filtermicrofluidic chipquantitative separationwhole-blood

Identifiers

PMID38793192
PMCPMC11122923

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.