Evidence map›Paper›PMID 38793132›Full record

ArticleMicromachines2024

Recent Developments in Magnetic Hyperthermia Therapy (MHT) and Magnetic Particle Imaging (MPI) in the Brain Tumor Field: A Scoping Review and Meta-Analysis.

Frederika Rentzeperis, Daniel Rivera, Jack Y Zhang, Cole Brown, Tirone Young, Benjamin Rodriguez, Alexander Schupper, Gabrielle Price, Jack Gomberg, Tyree Williams and 2 more

Abstract readScoping Review
In one paragraph

Article in Micromachines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Frederika RentzeperisDepartment of Medical Education, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0001-9797-1134
Daniel RiveraDepartment of Medical Education, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Jack Y ZhangDepartment of Medical Education, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-8389-2387
Cole BrownDepartment of Medical Education, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-4805-0042
Tirone YoungDepartment of Medical Education, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Benjamin RodriguezDepartment of Medical Education, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-4735-4773
Alexander SchupperDepartment of Neurological Surgery, Mount Sinai Hospital, New York, NY 10029, USA.
Gabrielle PriceDepartment of Medical Education, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Jack GombergDepartment of Medical Education, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-1688-7390
Tyree WilliamsSinai BioDesign, Department of Neurosurgery, Mount Sinai, New York, NY 10029, USA.
Alexandros BourasBrain Tumor Nanotechnology Laboratory, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA.
Constantinos HadjipanayisBrain Tumor Nanotechnology Laboratory, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA.

Funding

Mount Sinai Medical Scientist Training ProgramT32GM146636 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Talia H Swartz · 2022 to 2026
$6.8M
NIGMS NIH HHS T32 GM146636
6 · The paper itself

Abstract

Magnetic hyperthermia therapy (MHT) is a promising treatment modality for brain tumors using magnetic nanoparticles (MNPs) locally delivered to the tumor and activated with an external alternating magnetic field (AMF) to generate antitumor effects through localized heating. Magnetic particle imaging (MPI) is an emerging technology offering strong signal-to-noise for nanoparticle localization. A scoping review was performed by systematically querying Pubmed, Scopus, and Embase. In total, 251 articles were returned, 12 included. Articles were analyzed for nanoparticle type used, MHT parameters, and MPI applications. Preliminary results show that MHT is an exciting treatment modality with unique advantages over current heat-based therapies for brain cancer. Effective application relies on the further development of unique magnetic nanoparticle constructs and imaging modalities, such as MPI, that can enable real-time MNP imaging for improved therapeutic outcomes.

Indexed as

astrocytomaglioblastomagliomahyperthermiamagnetic hyperthermia therapymagnetic particle imagingnanoparticles

Identifiers

PMID38793132
PMCPMC11123314

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.