Evidence map›Paper›PMID 38793112›Full record

ArticleJournal of personalized medicine2024

Iris Pigmented Lesions and Risk of Cutaneous Melanoma: Case-Control Study in Lithuania.

Lukas Šemeklis, Laura Kapitanovaitė, Grinvydas Butrimas, Kamilija Briedė, Augustė Dubinskaitė, Reda Žemaitienė, Skaidra Valiukevičienė

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lukas ŠemeklisDepartment of Ophthalmology, Medical Academy, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.ORCID 0000-0001-7001-1782
Laura KapitanovaitėDepartment of Ophthalmology, Medical Academy, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.ORCID 0009-0008-6426-7616
Grinvydas ButrimasDepartment of Skin and Venereal Diseases, Medical Academy, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.
Kamilija BriedėDepartment of Skin and Venereal Diseases, Medical Academy, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.ORCID 0000-0002-0562-6403
Augustė DubinskaitėFaculty of Medicine, Medical Academy, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.
Reda ŽemaitienėDepartment of Ophthalmology, Medical Academy, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.
Skaidra ValiukevičienėDepartment of Skin and Venereal Diseases, Medical Academy, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.ORCID 0000-0003-1219-5928

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global incidence of cutaneous melanoma (CM) is rising, necessitating early detection and identification of risk factors across different populations. A case-control study with 180 patients with primary diagnosed CM and 182 healthy controls was conducted. Participants underwent ophthalmic and skin examinations, where the identification and counting of common melanocytic nevi (CMN) and atypical melanocytic nevi (AMN) was performed. During ophthalmic examination, high-resolution slit lamp iris images were taken. Images were categorized according to iris periphery, collaret, and freckles. There was no difference in iris periphery and collaret color between groups. However, blue/grey iris periphery and blue collaret with or without freckles were the most common patterns. The presence of pigmented iris lesions and 2-5 mm and ≥5 mm in diameter CMNs was strongly associated with CM risk. The evidence from this study indicates that blue or grey periphery and blue collaret iris pattern with iris freckles are 2.74 times higher in the CM group than controls. Further research is needed to explore iris patterns' association with CM risk in diverse populations.

Indexed as

cutaneous melanomairis frecklesiris patternsiris pigmented lesions

Identifiers

PMID38793112
PMCPMC11122085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.