Observational studyMedicina (Kaunas, Lithuania)2024
Major Bleeding Events in Hospitalized COVID-19 Patients: A Retrospective Observational Study.
Andrea Poloni, Giacomo Casalini, Giacomo Pozza, Andrea Giacomelli, Marta Colaneri, Giorgia Carrozzo, Beatrice Caloni, Cosmin Lucian Ciubotariu, Martina Zacheo, Andrea Rabbione and 7 more
Abstract readObservational Study
In one paragraphObservational study in Medicina (Kaunas, Lithuania), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
17 authors.
Andrea PoloniDepartment of Biomedical and Clinical Sciences, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0002-6765-8101 Giacomo CasaliniIII Infectious Diseases Unit, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, 20157 Milan, Italy.
Giacomo PozzaDepartment of Biomedical and Clinical Sciences, Università degli Studi di Milano, 20122 Milan, Italy.
Andrea GiacomelliDepartment of Biomedical and Clinical Sciences, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0003-3685-4289 Marta ColaneriII Infectious Diseases Unit, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, 20157 Milan, Italy.ORCID 0000-0002-5939-9576 Giorgia CarrozzoDepartment of Biomedical and Clinical Sciences, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0009-0006-2752-9053 Beatrice CaloniDepartment of Biomedical and Clinical Sciences, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0009-0008-8823-6910 Cosmin Lucian CiubotariuDepartment of Biomedical and Clinical Sciences, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0009-0003-3607-1847 Martina ZacheoDepartment of Biomedical and Clinical Sciences, Università degli Studi di Milano, 20122 Milan, Italy.
Andrea RabbioneDepartment of Biomedical and Clinical Sciences, Università degli Studi di Milano, 20122 Milan, Italy.
Margherita PieruzziDepartment of Biomedical and Clinical Sciences, Università degli Studi di Milano, 20122 Milan, Italy.
Federico BaroneDepartment of Biomedical and Clinical Sciences, Università degli Studi di Milano, 20122 Milan, Italy.
Matteo PasseriniII Infectious Diseases Unit, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, 20157 Milan, Italy.ORCID 0000-0002-8120-1853 Anna Lisa RidolfoIII Infectious Diseases Unit, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, 20157 Milan, Italy.ORCID 0000-0003-1106-6219 Giuliano RizzardiniI Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, 20157 Milan, Italy.
Andrea GoriDepartment of Biomedical and Clinical Sciences, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0001-6587-4794 Spinello AntinoriDepartment of Biomedical and Clinical Sciences, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0003-0569-9407 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Thromboprophylaxis/anticoagulation treatment is often required in hospitalized COVID-19 patients. We aimed to estimate the prevalence of major bleeding events in hospitalized COVID-19 patients. This was a retrospective observational study including all COVID-19 hospitalized patients ≥18 years of age at one reference center in northern Italy. The crude prevalence (between February 2020-2022) of major bleeding events was estimated as the number of major bleeding episodes divided by patients at risk. Uni- and multivariable Cox models were built to assess factors potentially associated with major bleeding events. Twenty-nine (0.98%) out of 2,945 COVID-19 patients experienced a major bleeding event [prevalence of 0.55% (95%CI 0.37-0.79)], of which five were fatal. Patients who experienced a major bleeding event were older [78 years (72-84 IQR) vs. 67 years (55-78 IQR),
Indexed as
COVID-19HemorrhageHospitalizationAgedAged, 80 and overAge FactorsAnticoagulantsFemaleHumansItalyMaleMiddle AgedPrevalenceProportional Hazards ModelsRetrospective StudiesRisk FactorsAnticoagulantsageanticoagulantantiplateletfatal bleedingSARS-CoV-2
Identifiers
PMID38792997
PMCPMC11122796
What OpenQuestion holds
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