Differential Epigenetic Regulation in Uninfected and Tuberculosis-Human Immunodeficiency Virus Co-Infected Patients.

Katlego Mamabolo, Reubina Wadee, Yvonne Perner, Pumza Magangane, Sanelisiwe Thinasonke Duze, Musa Marimani

Abstract read

In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Epigenetic Reprogramming byAntibiotics (Basel, Switzerland) · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katlego MamaboloAnatomical Pathology, School of Pathology, Health Sciences, University of the Witwatersrand, Johannesburg 2001, South Africa.

Reubina WadeeAnatomical Pathology, School of Pathology, Health Sciences, University of the Witwatersrand, Johannesburg 2001, South Africa.ORCID 0000-0002-5981-4450

Yvonne PernerAnatomical Pathology, School of Pathology, Health Sciences, University of the Witwatersrand, Johannesburg 2001, South Africa.

Pumza MaganganeAnatomical Pathology, School of Pathology, Health Sciences, University of the Witwatersrand, Johannesburg 2001, South Africa.ORCID 0000-0002-4954-5576

Sanelisiwe Thinasonke DuzeClinical Microbiology and Infectious Diseases, School of Pathology, Health Sciences, University of the Witwatersrand, Johannesburg 2001, South Africa.ORCID 0000-0002-3909-4628

Musa MarimaniAnatomical Pathology, School of Pathology, Health Sciences, University of the Witwatersrand, Johannesburg 2001, South Africa.

Funding

Carnegie DTA research grant RKSMM21 for Musa MarimaniCarnegie DTA research grant RKSST23 for Sanelisiwe Thinasonke DuzeNational Research Foundation of South Africa Thuthuka 138279 for Sanelisiwe Thinasonke DuzeNational Research Foundation of South Africa Thuthuka 138302 for Musa Marimani

6 · The paper itself

Abstract

This study aimed to compare the degree of epigenetic modifications between a TB-HIV co-infected cohort and uninfected subjects. Formalin-fixed paraffin-embedded (FFPE) tissues were retrieved from 45 TB-HIV co-infected and 45 control individuals. Real-time PCR was applied to compare the level of expression of genes involved in epigenetic regulation. The protein multiplex assay was used to assess the degree of protein modification. DNA sequencing was used to determine the evolutionary relationships between the infecting HIV and

Indexed as

AIDSepigeneticsgene expressionHIVMtbTB

Identifiers

PMID38792830

DOI10.3390/microorganisms12051001

PMCPMC11123988

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.