Evidence map›Paper›PMID 38792679›Full record

ArticleMicroorganisms2024

Prosthetic Joint Infections Caused by

Alvaro Auñon, Llanos Salar-Vidal, Ignacio Mahillo-Fernandez, Francisco Almeida, Pedro Pereira, Jaime Lora-Tamayo, Tristan Ferry, Sarah Souèges, Aurélien Dinh, Rosa Escudero and 4 more

Abstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alvaro AuñonIIS-Fundacion Jimenez Diaz, UAM, Av. Reyes Catolicos 2, 28040 Madrid, Spain.ORCID 0000-0003-3771-5598
Llanos Salar-VidalIIS-Fundacion Jimenez Diaz, UAM, Av. Reyes Catolicos 2, 28040 Madrid, Spain.ORCID 0000-0002-3052-0176
Ignacio Mahillo-FernandezIIS-Fundacion Jimenez Diaz, UAM, Av. Reyes Catolicos 2, 28040 Madrid, Spain.ORCID 0000-0003-0558-6541
Francisco AlmeidaHospital de São João, 4200-319 Porto, Portugal.ORCID 0000-0001-6738-9434
Pedro PereiraHospital de São João, 4200-319 Porto, Portugal.ORCID 0000-0003-0183-8756
Jaime Lora-TamayoCIBERINFEC, 28029 Madrid, Spain.
Tristan FerryESCMID Study Group for Implant-Associated Infections (ESGIAI), Aeschenvorstadt 55, 4051 Basel, Switzerland.
Sarah SouègesCHU-Hopital Croix Rousse, 69317 Lyon, France.
Aurélien DinhESCMID Study Group for Implant-Associated Infections (ESGIAI), Aeschenvorstadt 55, 4051 Basel, Switzerland.
Rosa EscuderoCIBERINFEC, 28029 Madrid, Spain.ORCID 0000-0001-5736-8111
Candela Menéndez Fernández-MirandaHUCA, 33011 Oviedo, Spain.ORCID 0009-0001-0443-1073
Alicia RicoCIBERINFEC, 28029 Madrid, Spain.ORCID 0000-0002-4364-2973
Nicolo RossiESCMID Study Group for Implant-Associated Infections (ESGIAI), Aeschenvorstadt 55, 4051 Basel, Switzerland.
Jaime EstebanIIS-Fundacion Jimenez Diaz, UAM, Av. Reyes Catolicos 2, 28040 Madrid, Spain.ORCID 0000-0002-8971-3167

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWhile tuberculosis remains a significant global health concern, prosthetic joint infections (PJIs) caused by members of the

methodsThe ESGIAI and ESGMYC study groups were used to collect information on non-published cases of tuberculous prosthetic joint infections (PJIs). Additionally, a literature review of all published cases of tuberculous PJIs was conducted. All identified cases in the retrospective study and in the literature review were merged and included in the statistical analysis, involving both univariate and multivariate analyses.

resultsFifteen previously unreported cases of tuberculous prosthetic joint infections (PJIs) from four countries were detailed. Among them, ten patients were female, with a median age of 76 years. The hip was affected in 13 cases. Seven patients experienced co-infection with another microorganism. Treatment approaches varied, with 13 patients undergoing implant removal, one treated with DAIR (debridement, antibiotics, and implant retention), and one case was treated with an unknown treatment method. All patients received antibiotic therapy and achieved a cure. The literature review that was conducted detected 155 published cases. Univariate analysis revealed a statistical significance for previous tuberculosis, joint, and no importance of surgery for cure.

conclusionsTuberculous prosthetic joint infection (PJI) is a rare condition, typically presenting as a localized chronic infection. Antibiotic treatment is essential for the management of these patients, but neither surgical treatment nor duration of treatment seems to have importance in the outcome.

Indexed as

durationoutcomeprosthetic joint infectionsurgerytreatmenttuberculosis

Identifiers

PMID38792679
PMCPMC11123809

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.