Evidence map›Paper›PMID 38792657›Full record

ArticleLife (Basel, Switzerland)2024

Myelodysplastic Syndrome: Clinical Characteristics and Significance of Preclinically Detecting Biallelic Mutations in the

Anastasiia Danishevich, Anzhelika Chegodar, Natalia Bodunova, Fedor Konovalov, Maria Nefedova, Natalya Kremneva, Nizhat Kurbanov, Airat Bilyalov, Sergey Nikolaev, Igor Khatkov and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anastasiia DanishevichThe Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.
Anzhelika ChegodarThe Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.ORCID 0000-0001-7753-3698
Natalia BodunovaThe Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.
Fedor KonovalovIndependent Clinical Bioinformatics Laboratory, 123181 Moscow, Russia.ORCID 0000-0001-6414-436X
Maria NefedovaIndependent Clinical Bioinformatics Laboratory, 123181 Moscow, Russia.
Natalya KremnevaThe Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.
Nizhat KurbanovThe Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.
Airat BilyalovThe Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.ORCID 0000-0002-8888-8395
Sergey NikolaevThe Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.ORCID 0000-0003-0673-3590
Igor KhatkovThe Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.
Galina DudinaThe Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myelodysplastic syndrome (MDS) is a clonal disease derived from hematopoietic stem cells, characterized by ineffective hematopoiesis (resulting in peripheral blood cytopenia) and an increased risk of transformation into acute myeloid leukemia. MDS is caused by a complex combination of genetic mutations resulting in a heterogeneous genotype. Genetic studies have identified a set of aberrations that play a central role in the pathogenesis of MDS. In this article, we present a clinical case of MDS transformation into acute myeloid leukemia in the context of two cell lines exhibiting morphological, immunophenotypic, and dysmyelopoiesis markers and the presence of two heterozygous mutations in the

Indexed as

myelodysplastic syndromeNGSTET2

Identifiers

PMID38792657
PMCPMC11122331

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.