Evidence map›Paper›PMID 38792606›Full record

ArticleLife (Basel, Switzerland)2024

Characteristics of Gut Microbiota in Rosacea Patients-A Cross-Sectional, Controlled Pilot Study.

Anne Guertler, Pascal Hering, Cátia Pacífico, Nikolaus Gasche, Barbara Sladek, Miriam Irimi, Lars E French, Benjamin M Clanner-Engelshofen, Markus Reinholz

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anne GuertlerDepartment of Dermatology and Allergy, LMU University Hospital Munich, 80337 Munich, Germany.ORCID 0000-0001-6865-0526
Pascal HeringDepartment of Dermatology and Allergy, LMU University Hospital Munich, 80337 Munich, Germany.
Cátia PacíficoBiome Diagnostics GmbH, 1200 Vienna, Austria.
Nikolaus GascheBiome Diagnostics GmbH, 1200 Vienna, Austria.ORCID 0000-0002-2811-1656
Barbara SladekBiome Diagnostics GmbH, 1200 Vienna, Austria.
Miriam IrimiDepartment of Dermatology and Allergy, LMU University Hospital Munich, 80337 Munich, Germany.
Lars E FrenchDepartment of Dermatology and Allergy, LMU University Hospital Munich, 80337 Munich, Germany.
Benjamin M Clanner-EngelshofenDepartment of Dermatology and Allergy, LMU University Hospital Munich, 80337 Munich, Germany.
Markus ReinholzDepartment of Dermatology and Allergy, LMU University Hospital Munich, 80337 Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent studies have suggested a possible connection between rosacea and patients' gut microbiota.

objectiveTo investigate the differences in fecal microbial profiles between patients with rosacea and healthy controls.

methodsGut microbiota of 54 rosacea patients (RP) were analyzed using MiSeq 16S rRNA sequencing. Enterotypes, the Firmicutes/Bacteroides (F/B) ratio, the significance of alpha and beta diversity, and differential abundance analysis (DAA) were calculated and compared with age- and gender-matched controls (CP,

resultsSignificant changes in the enterotypes and F/B ratio were observed between the RP and CP (

conclusionSignificant alterations in gut microbiota were present in the RP. Taxonomic shifts and reduced richness and diversity were observed when compared to the CP. Larger prospective studies are needed to investigate correlations with clinical features and to translate these findings into future therapeutic approaches.

Indexed as

dietdiversityenterotypesgut–skin axisnutritionstool

Identifiers

PMID38792606
PMCPMC11122217

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.