ReviewJournal of clinical medicine2024
Leukocytospermia and/or Bacteriospermia: Impact on Male Infertility.
Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- An automatic semen processing system versus a manual method for semen processing: a randomized, single-blind non-inferiority trial.Frontiers in endocrinology · 2026Trial
- Sertoli cell oxidative stress as a convergent hazard endpoint for environmental toxicants: A systematic review, meta-analysis, and AOP-based assessment.Redox biology · 2026Review
- Inefficacy ofAnimals : an open access journal from MDPI · 2026Article
- Trace Element Dyshomeostasis as a Mediator of Toxic Metal-Induced Reproductive Dysfunction: Mechanistic Insights and Future Perspectives.Biological trace element research · 2026Review
- Association Between Leukocytospermia and Varicocele in Patients With Infertility.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Review
- Oxidative Stress and Male Infertility: A Critical Analysis of Current Diagnostic and Therapeutic Methods.Antioxidants (Basel, Switzerland) · 2026Review
- Protective Effect of Intracellular Compounds of Lactobacillus plantarum on Goat Sperm Quality During Cryopreservation.Veterinary medicine and science · 2026Article
- Prostatitis-Related Male Infertility: From Inflammation and Dysbiosis to Sperm DNA Damage.Diagnostics (Basel, Switzerland) · 2026Review
- Oxidative Stress, Sperm DNA Fragmentation, or Both? Optimizing Test Selection in Male Infertility Evaluation.Antioxidants (Basel, Switzerland) · 2026Review
- Oxidative Stress and Inflammatory Biomarkers in Male Infertility: A Narrative Review of Diagnostic Value and Clinical Integration.Diagnostics (Basel, Switzerland) · 2026Review
- Seminal Interleukin-6 as a Biomarker of Inflammation, Oxidative Stress, and Sperm Dysfunction in Infertile Men.Diseases (Basel, Switzerland) · 2026Article
- Mechanisms of oxidative stress-induced sperm dysfunction.Frontiers in endocrinology · 2025Review
- Reliable Detection of Excessive Sperm Ros Production in Subfertile Patients: How Many Men with Oxidative Stress?Antioxidants (Basel, Switzerland) · 2024Article
- Oxidative Stress-Associated Male Infertility: Current Diagnostic and Therapeutic Approaches.Medicina (Kaunas, Lithuania) · 2024Review
- Total Round Cell Concentration in Semen and Its Association With Sperm DNA Fragmentation Index Among Ghanaian Males in Kumasi.American journal of men's healthArticle
- Inflammation and Oxidative Stress in Male Infertility: A Narrative Review.Reproductive medicine and biologyReview
- Asymptomatic Leukocytospermia and Assisted Reproductive Technology Outcomes: Reason for concern?International braz j urol : official journal of the Brazilian Society of UrologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infertility is a globally underestimated public health concern affecting almost 190 million people, i.e., about 17.5% of people during their lifetime, while the prevalence of male factor infertility is about 7%. Among numerous other causes, the prevalence of male genital tract infections reportedly ranges between 10% and 35%. Leukocytospermia is found in 30% of infertile men and up to 20% in fertile men. Bacterial infections cause an inflammatory response attracting leukocytes, which produce reactive oxygen species (ROS) and release cytokines, both of which can cause damage to sperm, rendering them dysfunctional. Although leukocytospermia and bacteriospermia are both clinical conditions that can negatively affect male fertility, there is still debate about their impact on assisted reproduction outcomes and management. According to World Health Organization (WHO) guidelines, leukocytes should be determined by means of the Endtz test or with monoclonal antibodies against CD15, CD68 or CD22. The cut-off value proposed by the WHO is 1 × 10
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.