Evidence map›Paper›PMID 38792347›Full record

ArticleJournal of clinical medicine2024

Reconstruction of Craniomaxillofacial Bone Defects with 3D-Printed Bioceramic Implants: Scoping Review and Clinical Case Series.

Maarten Verbist, Anne-Laure Vandevelde, Joris Geusens, Yi Sun, Eman Shaheen, Robin Willaert

Abstract readScoping Review
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
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  4. Article
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  7. Article
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  9. Recent Advances in Silk Fibroin Derived fromJournal of functional biomaterials · 2025
    Review
  10. Article
  11. Review
  12. Review
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  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maarten VerbistDepartment of Oral and Maxillofacial Surgery, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-9824-0269
Anne-Laure VandeveldeDepartment of Oral and Maxillofacial Surgery, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0009-0005-5121-8450
Joris GeusensDepartment of Oral and Maxillofacial Surgery, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-8706-671X
Yi SunDepartment of Oral and Maxillofacial Surgery, University Hospitals Leuven, 3000 Leuven, Belgium.
Eman ShaheenDepartment of Oral and Maxillofacial Surgery, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-6309-3791
Robin WillaertDepartment of Oral and Maxillofacial Surgery, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0003-1610-6988

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reconstruction of craniomaxillofacial bone defects using 3D-printed hydroxyapatite (HA) bioceramic patient-specific implants (PSIs) is a new technique with great potential. This study aimed to investigate the advantages, disadvantages, and clinical outcomes of these implants in craniomaxillofacial surgeries. The PubMed and Embase databases were searched for patients with craniomaxillofacial bone defects treated with bioceramic PSIs. Clinical outcomes such as biocompatibility, biomechanical properties, and aesthetics were evaluated and compared to those of commonly used titanium or poly-ether-ether-ketone (PEEK) implants and autologous bone grafts. Two clinical cases are presented to illustrate the surgical procedure and clinical outcomes of HA bioceramic PSIs. Literature review showed better a biocompatibility of HA PSIs than titanium and PEEK. The initial biomechanical properties were inferior to those of autologous bone grafts, PEEK, and titanium but improved when integrated. Satisfactory aesthetic results were found in our two clinical cases with good stability and absence of bone resorption or infection. Radiological signs of osteogenesis were observed in the two clinical cases six months postoperatively. HA bioceramic PSIs have excellent biocompatible properties and imitate natural bone biomechanically and radiologically. They are a well-suited alternative for conventional biomaterials in the reconstruction of load-sharing bone defects in the craniomaxillofacial region.

Indexed as

bioceramicsbone graftshydroxyapatitepatient-specific implantsplastic surgeryreconstructive surgical proceduresthree-dimensional printing

Identifiers

PMID38792347
PMCPMC11122134

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.