Evidence map›Paper›PMID 38792269›Full record

ArticleMolecules (Basel, Switzerland)2024

Anticancer Activity and Molecular Mechanisms of Acetylated and Methylated Quercetin in Human Breast Cancer Cells.

Kozue Sakao, Shihomi Hamamoto, Daigo Urakawa, Ziyu He, De-Xing Hou

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Advances in quercetin-based therapeutics for breast cancer: natural, synthetic, and nanotechnology-driven approaches.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Quercetin: A Natural Ally in Combating Breast Cancer.International journal of nanomedicine · 2025
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kozue SakaoThe United Graduate School of Agriculture Sciences, Kagoshima University, Kagoshima 890-0065, Japan.ORCID 0000-0001-5182-8121
Shihomi HamamotoGraduate School of Agriculture, Forestry and Fisheries, Kagoshima University, Kagoshima 890-0065, Japan.
Daigo UrakawaThe United Graduate School of Agriculture Sciences, Kagoshima University, Kagoshima 890-0065, Japan.
Ziyu HeThe United Graduate School of Agriculture Sciences, Kagoshima University, Kagoshima 890-0065, Japan.ORCID 0000-0001-6254-2057
De-Xing HouThe United Graduate School of Agriculture Sciences, Kagoshima University, Kagoshima 890-0065, Japan.

Funding

Japan Society for the Promotion of Science JP19K05931, JP16K1870
6 · The paper itself

Abstract

Quercetin, a flavonoid polyphenol found in many plants, has garnered significant attention due to its potential cancer chemoprevention. Our previous studies have shown that acetyl modification of the hydroxyl group of quercetin altered its antitumor effects in HepG2 cells. However, the antitumor effect in other cancer cells with different gene mutants remains unknown. In this study, we investigated the antitumor effect of quercetin and its methylated derivative 3,3',4',7-

Indexed as

ApoptosisBreast NeoplasmsCell ProliferationQuercetinAcetylationAntineoplastic AgentsCaspase 3Cell Line, TumorFemaleHumansMCF-7 CellsMethylationTumor Suppressor Protein p53Antineoplastic AgentsCaspase 3QuercetinTumor Suppressor Protein p53acetylationanticancerbreast cancermethylationquercetinquercetin derivatives

Identifiers

PMID38792269
PMCPMC11124128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.