Evidence map›Paper›PMID 38792236›Full record

ReviewMolecules (Basel, Switzerland)2024

Natural Product-Derived Phytochemicals for Influenza A Virus (H1N1) Prevention and Treatment.

Ruichen Li, Qianru Han, Xiaokun Li, Xinguang Liu, Weijie Jiao

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruichen LiCollege of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450003, China.
Qianru HanForeign Language Education Department, Zhengzhou Shuqing Medical College, Zhengzhou 450064, China.
Xiaokun LiCollege of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450003, China.
Xinguang LiuCo-Construction Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases by Henan & Education Ministry of China, Zhengzhou 450003, China.
Weijie JiaoCollege of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450003, China.

Funding

National Natural Science Foundation of China 82274274Scientific research project of Traditional Chinese Medicine in Henan Province 20-21Z3012Traditional Chinese Medicine Research of Corona Virus Disease 2019 Project 2022ZYFY06
6 · The paper itself

Abstract

Influenza A (H1N1) viruses are prone to antigenic mutations and are more variable than other influenza viruses. Therefore, they have caused continuous harm to human public health since the pandemic in 2009 and in recent times. Influenza A (H1N1) can be prevented and treated in various ways, such as direct inhibition of the virus and regulation of human immunity. Among antiviral drugs, the use of natural products in treating influenza has a long history, and natural medicine has been widely considered the focus of development programs for new, safe anti-influenza drugs. In this paper, we focus on influenza A (H1N1) and summarize the natural product-derived phytochemicals for influenza A virus (H1N1) prevention and treatment, including marine natural products, flavonoids, alkaloids, terpenoids and their derivatives, phenols and their derivatives, polysaccharides, and derivatives of natural products for prevention and treatment of influenza A (H1N1) virus. We further discuss the toxicity and antiviral mechanism against influenza A (H1N1) as well as the druggability of natural products. We hope that this review will facilitate the study of the role of natural products against influenza A (H1N1) activity and provide a promising alternative for further anti-influenza A drug development.

Indexed as

Antiviral AgentsBiological ProductsInfluenza A Virus, H1N1 SubtypeInfluenza, HumanPhytochemicalsAnimalsFlavonoidsHumansAntiviral AgentsBiological ProductsFlavonoidsPhytochemicalsantiviral agentsH1N1influenza Anatural products

Identifiers

PMID38792236
PMCPMC11124286

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.