Evidence map›Paper›PMID 38792159›Full record

ArticleMolecules (Basel, Switzerland)2024

Synthesis of Bodipy-Tagged Galactoconjugates and Evaluation of Their Antibacterial Properties.

Chiara Maria Antonietta Gangemi, Maura Monforte, Antonino Arrigo, Paola Maria Bonaccorsi, Sabrina Conoci, Antonella Iaconis, Fausto Puntoriero, Domenico Franco, Anna Barattucci

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Advances in BODIPY Derivatives for Antibacterial Phototherapy.Angewandte Chemie (International ed. in English) · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chiara Maria Antonietta GangemiDipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università degli Studi di Messina, V.le F. Stagno D'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0002-6978-1779
Maura MonforteDipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università degli Studi di Messina, V.le F. Stagno D'Alcontres 31, 98166 Messina, Italy.
Antonino ArrigoDipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università degli Studi di Messina, V.le F. Stagno D'Alcontres 31, 98166 Messina, Italy.ORCID 0009-0007-0781-3580
Paola Maria BonaccorsiDipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università degli Studi di Messina, V.le F. Stagno D'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0002-7914-5653
Sabrina ConociDipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università degli Studi di Messina, V.le F. Stagno D'Alcontres 31, 98166 Messina, Italy.
Antonella IaconisDipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università degli Studi di Messina, V.le F. Stagno D'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0002-4582-4850
Fausto PuntorieroDipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università degli Studi di Messina, V.le F. Stagno D'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0001-8579-859X
Domenico FrancoDipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università degli Studi di Messina, V.le F. Stagno D'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0002-2104-5465
Anna BarattucciDipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università degli Studi di Messina, V.le F. Stagno D'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0002-2415-5483

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a development of our research on biocompatible glycoconjugate probes and specifically multi-chromophoric systems, herein, we report the synthesis and early bactericidal tests of two luminescent glycoconjugates whose basic structure is characterized by two boron dipyrromethene difluoride (BODIPY) moieties and three galactoside rings mounted on an oligophenylene ethynylene (OPE) skeleton. BODIPY fluorophores have found widespread application in many branches of biology in the last few decades. In particular, molecular platforms showing two different BODIPY groups have unique photophysical behavior useful in fluorescence imaging. Construction of the complex architecture of the new probes is accomplished through a convergent route that exploits a series of copper-free Heck-Cassar-Sonogashira cross-couplings. The great emergency due to the proliferation of bacterial infections, in conjunction with growing antibiotic resistance, requires the production of new multifunctional drugs and efficient methods for their targeted delivery to control bacteria-associated diseases. Preliminary studies of the glycoconjugate properties as antibacterial agents against representatives of Gram-negative (

Indexed as

Anti-Bacterial AgentsBoron CompoundsMicrobial Sensitivity TestsPseudomonas aeruginosaFluorescent DyesGlycoconjugatesMolecular StructureStaphylococcus aureus4,4-difluoro-4-bora-3a,4a-diaza-s-indaceneAnti-Bacterial AgentsBoron CompoundsFluorescent DyesGlycoconjugatesantibacterialsBODIPYgalactoconjugateluminescence

Identifiers

PMID38792159
PMCPMC11124175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.