Evidence map›Paper›PMID 38792101›Full record

ArticleMolecules (Basel, Switzerland)2024

The Effect of Methyl-Derivatives of Flavanone on MCP-1, MIP-1β, RANTES, and Eotaxin Release by Activated RAW264.7 Macrophages.

Małgorzata Kłósek, Anna Kurek-Górecka, Radosław Balwierz, Agnieszka Krawczyk-Łebek, Edyta Kostrzewa-Susłow, Joanna Bronikowska, Dagmara Jaworska, Zenon P Czuba

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Targeted drug delivery systems for atherosclerosis.Journal of nanobiotechnology · 2025
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Małgorzata KłósekDepartment of Microbiology and Immunology, Faculty of Medical Sciences, Medical University of Silesia in Katowice, Jordana 19, 41-808 Zabrze, Poland.ORCID 0000-0002-9266-2292
Anna Kurek-GóreckaDepartment of Community Pharmacy, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, St Kasztanowa 3, 41-200 Sosnowiec, Poland.ORCID 0000-0002-2006-6715
Radosław BalwierzInstitute of Chemistry, University of Opole, Oleska 48, 45-052 Opole, Poland.ORCID 0000-0002-6173-2702
Agnieszka Krawczyk-ŁebekDepartment of Food Chemistry and Biocatalysis, University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland.ORCID 0000-0002-9507-0196
Edyta Kostrzewa-SusłowDepartment of Food Chemistry and Biocatalysis, University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland.ORCID 0000-0002-9259-0161
Joanna BronikowskaDepartment of Microbiology and Immunology, Faculty of Medical Sciences, Medical University of Silesia in Katowice, Jordana 19, 41-808 Zabrze, Poland.
Dagmara JaworskaDepartment of Microbiology and Immunology, Faculty of Medical Sciences, Medical University of Silesia in Katowice, Jordana 19, 41-808 Zabrze, Poland.ORCID 0000-0002-6796-3034
Zenon P CzubaDepartment of Microbiology and Immunology, Faculty of Medical Sciences, Medical University of Silesia in Katowice, Jordana 19, 41-808 Zabrze, Poland.ORCID 0000-0001-8216-4495

Funding

Medical University of Silesia BNW-1-057/K/3/O
6 · The paper itself

Abstract

Chemokines, also known as chemotactic cytokines, stimulate the migration of immune cells. These molecules play a key role in the pathogenesis of inflammation leading to atherosclerosis, neurodegenerative disorders, rheumatoid arthritis, insulin-resistant diabetes, and cancer. Moreover, they take part in inflammatory bowel disease (IBD). The main objective of our research was to determine the activity of methyl-derivatives of flavanone, namely, 2'-methylflavanone (

Indexed as

Chemokine CCL11Chemokine CCL2Chemokine CCL5FlavanonesMacrophagesAnimalsChemokine CCL4LipopolysaccharidesMacrophage ActivationMiceRAW 264.7 CellsCcl11 protein, mouseCcl2 protein, mouseCcl5 protein, mouseChemokine CCL11Chemokine CCL2Chemokine CCL4Chemokine CCL5FlavanonesLipopolysaccharideschemical structurechemokinesflavanoneinflammationmacrophages

Identifiers

PMID38792101
PMCPMC11123782

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.