Evidence map›Paper›PMID 38791933›Full record

ArticleCancers2024

Daratumumab during Myeloma Induction Therapy Is Associated with Impaired Stem Cell Mobilization and Prolonged Post-Transplant Hematologic Recovery.

Julian Mehl, Dilara Akhoundova, Ulrike Bacher, Barbara Jeker, Gaëlle Rhyner Agocs, Axel Ruefer, Susanne Soltermann, Martin Soekler, Annette Winkler, Michael Daskalakis and 1 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Rising Prevalence of Low-FrequencyCurrent issues in molecular biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Julian MehlDepartment of Medical Oncology, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.
Dilara AkhoundovaDepartment of Medical Oncology, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.ORCID 0000-0003-1639-3059
Ulrike BacherDepartment of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.ORCID 0000-0001-8771-947X
Barbara JekerDepartment of Medical Oncology, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.
Gaëlle Rhyner AgocsDepartment of Medical Oncology, HFR Fribourg-Hôpital Cantonal, 1708 Fribourg, Switzerland.
Axel RueferDepartment of Hematology, Cantonal Hospital Lucerne, 6000 Lucerne, Switzerland.
Susanne SoltermannDepartment of Oncology and Hematology, Bürgerspital Solothurn, 4500 Solothurn, Switzerland.
Martin SoeklerDepartment of Oncology and Hematology, Hospital Thun, 3600 Thun, Switzerland.
Annette WinklerDepartment of Oncology and Hematology, Biel Hospital Center, 2501 Biel, Switzerland.
Michael DaskalakisDepartment of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.ORCID 0000-0002-8138-0505
Thomas PabstDepartment of Medical Oncology, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.ORCID 0000-0002-6055-5257

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Daratumumab is being increasingly integrated into first-line multiple myeloma (MM) induction regimens, leading to improved response depth and longer progression-free survival. Autologous stem cell transplantation (ASCT) is commonly performed as a consolidation strategy following first-line induction in fit MM patients. We investigated a cohort of 155 MM patients who received ASCT after first-line induction with or without daratumumab (RVd,

Indexed as

anti-CD38 monoclonal antibodyapheresiscollectiondaratumumabengraftmentgemcitabinemobilizationmultiple myeloma (MM)vinorelbine

Identifiers

PMID38791933
PMCPMC11119719

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.