Evidence map›Paper›PMID 38791906›Full record

ArticleCancers2024

Speeding Up and Improving Image Quality in Glioblastoma MRI Protocol by Deep Learning Image Reconstruction.

Georg Gohla, Till-Karsten Hauser, Paula Bombach, Daniel Feucht, Arne Estler, Antje Bornemann, Leonie Zerweck, Eliane Weinbrenner, Ulrike Ernemann, Christer Ruff

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Georg GohlaDepartment of Diagnostic and Interventional Neuroradiology, Eberhard Karls-University Tübingen, 72076 Tübingen, Germany.ORCID 0000-0001-7596-5139
Till-Karsten HauserDepartment of Diagnostic and Interventional Neuroradiology, Eberhard Karls-University Tübingen, 72076 Tübingen, Germany.ORCID 0000-0001-7604-3419
Paula BombachDepartment of Neurology and Interdisciplinary Neuro-Oncology, University Hospital Tübingen, Hoppe-Seyler-Str. 3, 72076 Tübingen, Germany.
Daniel FeuchtDepartment of Neurosurgery, University Hospital Tübingen, Hoppe-Seyler-Str. 3, 72076 Tübingen, Germany.
Arne EstlerDepartment of Diagnostic and Interventional Neuroradiology, Eberhard Karls-University Tübingen, 72076 Tübingen, Germany.ORCID 0000-0002-1930-7497
Antje BornemannDepartment of Neuropathology, Institute of Pathology and Neuropathology, University Hospital Tübingen, Calwerstraße 3, 72076 Tübingen, Germany.
Leonie ZerweckDepartment of Diagnostic and Interventional Neuroradiology, Eberhard Karls-University Tübingen, 72076 Tübingen, Germany.ORCID 0000-0003-4105-5131
Eliane WeinbrennerDepartment of Diagnostic and Interventional Neuroradiology, Eberhard Karls-University Tübingen, 72076 Tübingen, Germany.
Ulrike ErnemannDepartment of Diagnostic and Interventional Neuroradiology, Eberhard Karls-University Tübingen, 72076 Tübingen, Germany.
Christer RuffDepartment of Diagnostic and Interventional Neuroradiology, Eberhard Karls-University Tübingen, 72076 Tübingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A fully diagnostic MRI glioma protocol is key to monitoring therapy assessment but is time-consuming and especially challenging in critically ill and uncooperative patients. Artificial intelligence demonstrated promise in reducing scan time and improving image quality simultaneously. The purpose of this study was to investigate the diagnostic performance, the impact on acquisition acceleration, and the image quality of a deep learning optimized glioma protocol of the brain. Thirty-three patients with histologically confirmed glioblastoma underwent standardized brain tumor imaging according to the glioma consensus recommendations on a 3-Tesla MRI scanner. Conventional and deep learning-reconstructed (DLR) fluid-attenuated inversion recovery, and T2- and T1-weighted contrast-enhanced Turbo spin echo images with an improved in-plane resolution, i.e., super-resolution, were acquired. Two experienced neuroradiologists independently evaluated the image datasets for subjective image quality, diagnostic confidence, tumor conspicuity, noise levels, artifacts, and sharpness. In addition, the tumor volume was measured in the image datasets according to Response Assessment in Neuro-Oncology (RANO) 2.0, as well as compared between both imaging techniques, and various clinical-pathological parameters were determined. The average time saving of DLR sequences was 30% per MRI sequence. Simultaneously, DLR sequences showed superior overall image quality (all

Indexed as

acceleration of acquisition timedeep learning-based reconstructiondiagnostic accuracyglioblastomaimage quality assessmentMRIRANO 2.0

Identifiers

PMID38791906
PMCPMC11119715

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.