Evidence map›Paper›PMID 38791602›Full record

ArticleInternational journal of molecular sciences2024

EGFR and PI3K Signalling Pathways as Promising Targets on Circulating Tumour Cells from Patients with Metastatic Gastric Adenocarcinoma.

Ann-Katrin Piper, Chelsea Penney, Jacqueline Holliday, Gary Tincknell, Yafeng Ma, Sarbar Napaki, Klaus Pantel, Daniel Brungs, Marie Ranson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ann-Katrin PiperSchool of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.ORCID 0000-0001-5805-0084
Chelsea PenneySchool of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
Jacqueline HollidaySchool of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
Gary TincknellSchool of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.ORCID 0000-0003-2611-0075
Yafeng MaCentre for Circulating Tumour Cell Diagnostics & Research at the Ingham Institute for Applied Medical Research, South-Western Clinical School, University of New South Wales, Liverpool, NSW 2170, Australia.ORCID 0000-0002-0522-8771
Sarbar NapakiGraduate School of Medicine, University of Wollongong, Wollongong, NSW 2522, Australia.
Klaus PantelInstitute for Tumor Biology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0001-5736-2772
Daniel BrungsMolecular Horizons, University of Wollongong, Wollongong, NSW 2522, Australia.
Marie RansonSchool of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.ORCID 0000-0002-5570-9645

Funding

Tour de Cure RSP-316-FY2023
6 · The paper itself

Abstract

The prognosis for metastatic gastric adenocarcinoma (mGAC) remains poor. Gene alterations in receptor tyrosine kinases (RTKs) such as epidermal growth factor receptor

Indexed as

AdenocarcinomaClass I Phosphatidylinositol 3-KinasesErbB ReceptorsNeoplastic Cells, CirculatingSignal TransductionStomach NeoplasmsAntineoplastic AgentsCell Line, TumorHumansNeoplasm MetastasisPhosphatidylinositol 3-KinasesPhosphoinositide-3 Kinase InhibitorsProtein Kinase InhibitorsThiazolesAlpelisibAntineoplastic AgentsClass I Phosphatidylinositol 3-KinasesEGFR protein, humanErbB ReceptorsPhosphatidylinositol 3-KinasesPhosphoinositide-3 Kinase InhibitorsPIK3CA protein, humanProtein Kinase InhibitorsThiazoles3D cell culturealpelisibcell signallingcirculating tumour cellsc-MetEGFRgastric cancergefitiniborganotypicsPI3K/AktPIK-75

Identifiers

PMID38791602
PMCPMC11122469

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.