Evidence map›Paper›PMID 38791334›Full record

ReviewInternational journal of molecular sciences2024

Evolution of Glutamate Metabolism via

Andreas Plaitakis, Kyriaki Sidiropoulou, Dimitra Kotzamani, Ionela Litso, Ioannis Zaganas, Cleanthe Spanaki

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andreas PlaitakisDepartment of Neurology, School of Health Sciences, Faculty of Medicine, University of Crete, Voutes, 71003 Heraklion, Crete, Greece.ORCID 0000-0002-3290-8254
Kyriaki SidiropoulouDepartment of Biology, University of Crete, Voutes, 71003 Heraklion, Crete, Greece.
Dimitra KotzamaniDepartment of Neurology, School of Health Sciences, Faculty of Medicine, University of Crete, Voutes, 71003 Heraklion, Crete, Greece.
Ionela LitsoDepartment of Neurology, School of Health Sciences, Faculty of Medicine, University of Crete, Voutes, 71003 Heraklion, Crete, Greece.
Ioannis ZaganasDepartment of Neurology, School of Health Sciences, Faculty of Medicine, University of Crete, Voutes, 71003 Heraklion, Crete, Greece.ORCID 0000-0002-0774-5772
Cleanthe SpanakiDepartment of Neurology, School of Health Sciences, Faculty of Medicine, University of Crete, Voutes, 71003 Heraklion, Crete, Greece.

Funding

European Union's Horizon 2020 program -Marie Skłodowska-Curie grant grant agreement No 101007926
6 · The paper itself

Abstract

Human evolution is characterized by rapid brain enlargement and the emergence of unique cognitive abilities. Besides its distinctive cytoarchitectural organization and extensive inter-neuronal connectivity, the human brain is also defined by high rates of synaptic, mainly glutamatergic, transmission, and energy utilization. While these adaptations' origins remain elusive, evolutionary changes occurred in synaptic glutamate metabolism in the common ancestor of humans and apes via the emergence of

Indexed as

CognitionGlutamate DehydrogenaseGlutamic AcidNeuronal PlasticityAnimalsEvolution, MolecularHippocampusHumansLactic AcidLong-Term PotentiationMiceMice, TransgenicPyramidal CellsSynapsesGLUD2 protein, humanGlutamate DehydrogenaseGlutamic AcidLactic AcidCA1/CA3 LTPGLUD2glutamatehuman brain evolutionlactatesynaptic plasticity

Identifiers

PMID38791334
PMCPMC11120665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.