Evidence map›Paper›PMID 38791322›Full record

ArticleInternational journal of molecular sciences2024

No Association of Polymorphisms in the Genes Encoding Interleukin-6 and Interleukin-6 Receptor Subunit Alpha with the Risk of Keloids in Polish Patients.

Andrzej Dmytrzak, Klaudyna Lewandowska, Agnieszka Boroń, Beata Łoniewska, Natalie Grzesch, Andrzej Brodkiewicz, Jeremy S C Clark, Andrzej Ciechanowicz, Dorota Kostrzewa-Nowak

Abstract read
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In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Special Issue: The Role of Cytokines in Disease.International journal of molecular sciences · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrzej DmytrzakAesthetic Med, 71-403 Szczecin, Poland.
Klaudyna LewandowskaDepartment of Clinical and Molecular Biochemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0002-6732-2341
Agnieszka BorońDepartment of Clinical and Molecular Biochemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0003-3574-5726
Beata ŁoniewskaDepartment of Neonatal Diseases, Pomeranian Medical University, 70-111 Szczecin, Poland.
Natalie GrzeschDepartment of Clinical and Molecular Biochemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.
Andrzej BrodkiewiczDepartment of Pediatrics, Child Nephrology, Dialysotherapy and Management of Acute Poisoning, Pomeranian Medical University, 70-780 Szczecin, Poland.
Jeremy S C ClarkDepartment of Clinical and Molecular Biochemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.
Andrzej CiechanowiczDepartment of Clinical and Molecular Biochemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0002-3804-440X
Dorota Kostrzewa-NowakDepartment of Clinical and Molecular Biochemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0001-7025-3087

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A keloid is a benign fibroproliferative hypertrophy of scar tissue that extends outside the original wound and invades adjacent healthy skin. Keloid formation is thought to be a complex process including overactivity of the interleukin-6 signaling pathway and genetic susceptibility. The aim of the study was to investigate possible associations between rs1800797, rs1800796, and rs1800795 polymorphisms in the promoter of the

Indexed as

Genetic Predisposition to DiseaseInterleukin-6KeloidPolymorphism, Single NucleotideReceptors, Interleukin-6AdolescentAdultAllelesCase-Control StudiesFemaleGene FrequencyGenetic Association StudiesGenotypeHaplotypesHumansInfant, NewbornIL6 protein, humanIL6R protein, humanInterleukin-6Receptors, Interleukin-6genetic associationsIL-6IL6IL6RIL-6RAkeloid

Identifiers

PMID38791322
PMCPMC11121548

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.