Evidence map›Paper›PMID 38791221›Full record

ArticleInternational journal of molecular sciences2024

Evaluation of the Inhibitory Potential of Synthetic Peptides Homologous to CDR3 Regions of a Monoclonal Antibody against Bothropic Venom Serine Proteases.

Lucas Yuri Saladini, Marcos Jorge Magalhães-Junior, Cristiane Castilho Fernandes da Silva, Priscila Gonçalves Coutinho Oliveira, Roberto Tadashi Kodama, Lais Gomes, Milton Yutaka Nishiyama-Jr, Patrick Jack Spencer, Wilmar Dias da Silva, Fernanda Calheta Vieira Portaro

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lucas Yuri SaladiniLaboratory of Structure and Function of Biomolecules, Butantan Institute, São Paulo 05503-900, Brazil.
Marcos Jorge Magalhães-JuniorLaboratory of Immunochemistry, Butantan Institute, São Paulo 05503-900, Brazil.
Cristiane Castilho Fernandes da SilvaLaboratory of Structure and Function of Biomolecules, Butantan Institute, São Paulo 05503-900, Brazil.
Priscila Gonçalves Coutinho OliveiraLaboratory of Structure and Function of Biomolecules, Butantan Institute, São Paulo 05503-900, Brazil.
Roberto Tadashi KodamaLaboratory of Structure and Function of Biomolecules, Butantan Institute, São Paulo 05503-900, Brazil.ORCID 0000-0003-0565-9018
Lais GomesLaboratory of Structure and Function of Biomolecules, Butantan Institute, São Paulo 05503-900, Brazil.ORCID 0000-0002-9961-2642
Milton Yutaka Nishiyama-JrLaboratory of Applied Toxinology, Center of Toxins, Immune-Response and Cell Signaling (CeTICS), Instituto Butantan, São Paulo 05503-900, Brazil.ORCID 0000-0002-2410-0562
Patrick Jack SpencerBiotechnology Center, Nuclear and Energy Research Institute (IPEN/CNEN/SP), São Paulo 05503-900, Brazil.
Wilmar Dias da SilvaLaboratory of Immunochemistry, Butantan Institute, São Paulo 05503-900, Brazil.
Fernanda Calheta Vieira PortaroLaboratory of Structure and Function of Biomolecules, Butantan Institute, São Paulo 05503-900, Brazil.ORCID 0000-0002-9582-4699

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/07467-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/20832-7National Council for Scientific and Technological Development 490048/2005-6
6 · The paper itself

Abstract

Snakebite accidents, neglected tropical diseases per the WHO, pose a significant public health threat due to their severity and frequency. Envenomation by

Indexed as

Antibodies, MonoclonalBothropsPeptidesSerine ProteasesAmino Acid SequenceAnimalsAntiveninsComplementarity Determining RegionsCrotalid VenomsSerine Proteinase InhibitorsAntibodies, MonoclonalAntiveninsComplementarity Determining RegionsCrotalid VenomsPeptidesSerine ProteasesSerine Proteinase Inhibitorsantibodiesantigeninhibitorspeptidessnakebites

Identifiers

PMID38791221
PMCPMC11121450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.