Evidence map›Paper›PMID 38791033›Full record

ArticleBiomedicines2024

Sequential Evaluation of Hematology Markers as a Prognostic Factor in Glioblastoma Patients.

João Meira Gonçalves, Bruno Carvalho, Rui Tuna, Patricia Polónia, Paulo Linhares

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Longitudinal analysis of systemic inflammatory biomarkers in glioblastoma patients: an exploratory single‑center analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

João Meira GonçalvesNeurosurgery Department, Centro Hospitalar Universitário São João, 4200-319 Oporto, Portugal.ORCID 0000-0001-9817-3900
Bruno CarvalhoNeurosurgery Department, Centro Hospitalar Universitário São João, 4200-319 Oporto, Portugal.ORCID 0000-0002-3972-7544
Rui TunaNeurosurgery Department, Centro Hospitalar Universitário São João, 4200-319 Oporto, Portugal.
Patricia PolóniaNeurosurgery Department, Centro Hospitalar Universitário São João, 4200-319 Oporto, Portugal.
Paulo LinharesNeurosurgery Department, Centro Hospitalar Universitário São João, 4200-319 Oporto, Portugal.ORCID 0000-0002-0888-3325

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In our study, we investigated the prognostic significance of hematological markers-NLR (Neutrophil-to-Lymphocyte Ratio), PLR (Platelet-to-Lymphocyte Ratio), and RDW-CV (Red Blood Cell Distribution Width-Coefficient of Variation)-in 117 glioblastoma patients. The data collected from January 2016 to December 2018 included demographics, clinical scores, and treatment regimens. Unlike previous research, which often examined these markers solely before surgery, our unique approach analyzed them at multiple stages: preoperative, postoperative, and before adjuvant therapies. We correlated these markers with the overall survival (OS) and progression-free survival (PFS) using statistical tools, including ANOVA, Cox regression, and Kaplan-Meier survival analyses, employing SPSS version 29.0. Our findings revealed notable variations in the NLR, PLR, and RDW-CV across different treatment stages. The NLR and PLR decreased after surgery, with some stabilization post-STUPP phase (NLR:

Indexed as

glioblastomahematology markersmonocyte-to-lymphocyte rationeutrophils-to-lymphocyte ratiooverall survivalplatelet-to-lymphocyte ratioprognostic markers

Identifiers

PMID38791033
PMCPMC11118025

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.