Evidence map›Paper›PMID 38791012›Full record

ReviewBiomedicines2024

Transient Left Ventricular Dysfunction from Cardiomyopathies to Myocardial Viability: When and Why Cardiac Function Recovers.

Giancarlo Trimarchi, Lucio Teresi, Roberto Licordari, Alessandro Pingitore, Fausto Pizzino, Patrizia Grimaldi, Danila Calabrò, Paolo Liotta, Antonio Micari, Cesare de Gregorio and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Giancarlo TrimarchiDepartment of Clinical and Experimental Medicine, Cardiology Unit, University of Messina, 98100 Messina, Italy.ORCID 0009-0008-9165-7732
Lucio TeresiDepartment of Clinical and Experimental Medicine, Cardiology Unit, University of Messina, 98100 Messina, Italy.
Roberto LicordariDepartment of Biomedical and Dental Sciences and Morphological and Functional Imaging, University of Messina, 98100 Messina, Italy.ORCID 0000-0003-3185-9240
Alessandro PingitoreIstituto di Fisiologia Clinica, Clinical Physiology Institute, CNR, 56124 Pisa, Italy.ORCID 0000-0002-4049-184X
Fausto PizzinoCardiology Unit, Heart Centre, Fondazione Gabriele Monasterio-Regione Toscana, 54100 Massa, Italy.ORCID 0000-0003-1053-8325
Patrizia GrimaldiDepartment of Clinical and Experimental Medicine, Cardiology Unit, University of Messina, 98100 Messina, Italy.
Danila CalabròDepartment of Clinical and Experimental Medicine, Cardiology Unit, University of Messina, 98100 Messina, Italy.
Paolo LiottaDepartment of Clinical and Experimental Medicine, Cardiology Unit, University of Messina, 98100 Messina, Italy.
Antonio MicariDepartment of Biomedical and Dental Sciences and Morphological and Functional Imaging, University of Messina, 98100 Messina, Italy.
Cesare de GregorioDepartment of Clinical and Experimental Medicine, Cardiology Unit, University of Messina, 98100 Messina, Italy.ORCID 0000-0003-3022-266X
Gianluca Di BellaDepartment of Clinical and Experimental Medicine, Cardiology Unit, University of Messina, 98100 Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transient left ventricular dysfunction (TLVD), a temporary condition marked by reversible impairment of ventricular function, remains an underdiagnosed yet significant contributor to morbidity and mortality in clinical practice. Unlike the well-explored atherosclerotic disease of the epicardial coronary arteries, the diverse etiologies of TLVD require greater attention for proper diagnosis and management. The spectrum of disorders associated with TLVD includes stress-induced cardiomyopathy, central nervous system injuries, histaminergic syndromes, various inflammatory diseases, pregnancy-related conditions, and genetically determined syndromes. Furthermore, myocardial infarction with non-obstructive coronary arteries (MINOCA) origins such as coronary artery spasm, coronary thromboembolism, and spontaneous coronary artery dissection (SCAD) may also manifest as TLVD, eventually showing recovery. This review highlights the range of ischemic and non-ischemic clinical situations that lead to TLVD, gathering conditions like Tako-Tsubo Syndrome (TTS), Kounis syndrome (KS), Myocarditis, Peripartum Cardiomyopathy (PPCM), and Tachycardia-induced cardiomyopathy (TIC). Differentiation amongst these causes is crucial, as they involve distinct clinical, instrumental, and genetic predictors that bode different outcomes and recovery potential for left ventricular function. The purpose of this review is to improve everyday clinical approaches to treating these diseases by providing an extensive survey of conditions linked with TLVD and the elements impacting prognosis and outcomes.

Indexed as

cardiomyopathiesleft ventricular function recoveryMINOCATako-Tsubo Syndrome (TTS)transient left ventricular dysfunctionviability

Identifiers

PMID38791012
PMCPMC11117605

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.