Evidence map›Paper›PMID 38791006›Full record

ArticleBiomedicines2024

Long-Term Structural Changes in the Osteochondral Unit in Patients with Osteoarthritis Undergoing Corrective Osteotomy with Platelet-Rich Plasma or Stromal Vascular Fraction Post-Treatment.

Aleksey Prizov, Elena Tchetina, Aleksey Volkov, Ilya Eremin, Nikolay Zagorodniy, Fedor Lazko, Andrey Pulin, Evgeniy Belyak, Konstantin Kotenko, Gulnora Eshmotova and 2 more

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Aleksey PrizovDepartment of Traumatology and Orthopaedics, RUDN University, Miklukho-Maklaya Str. 6, Moscow 117198, Russia.
Elena TchetinaImmunology and Molecular Biology Laboratory, Nasonova Research Institute of Rheumatology, Kashirskoe Shosse 34A, Moscow 115522, Russia.ORCID 0000-0001-7312-2349
Aleksey VolkovDepartment of Pathological Anatomy, RUDN University, Miklukho-Maklaya Str. 6, Moscow 117198, Russia.ORCID 0000-0002-5611-3990
Ilya EreminSurgery Department, Petrovsky National Research Center of Surgery, Abrikosovsky lane 2, Moscow 119435, Russia.
Nikolay ZagorodniyDepartment of Traumatology and Orthopaedics, RUDN University, Miklukho-Maklaya Str. 6, Moscow 117198, Russia.
Fedor LazkoDepartment of Traumatology and Orthopaedics, RUDN University, Miklukho-Maklaya Str. 6, Moscow 117198, Russia.
Andrey PulinPirogov National Medical and Surgical Center, Nizhnyaya Pervomayskaya Str. 70, Moscow 105203, Russia.
Evgeniy BelyakDepartment of Traumatology and Orthopaedics, RUDN University, Miklukho-Maklaya Str. 6, Moscow 117198, Russia.
Konstantin KotenkoSurgery Department, Petrovsky National Research Center of Surgery, Abrikosovsky lane 2, Moscow 119435, Russia.
Gulnora EshmotovaDepartment of Pathological Anatomy, RUDN University, Miklukho-Maklaya Str. 6, Moscow 117198, Russia.
Svetlana GlukhovaImmunology and Molecular Biology Laboratory, Nasonova Research Institute of Rheumatology, Kashirskoe Shosse 34A, Moscow 115522, Russia.ORCID 0000-0002-4285-0869
Aleksandr LilaImmunology and Molecular Biology Laboratory, Nasonova Research Institute of Rheumatology, Kashirskoe Shosse 34A, Moscow 115522, Russia.

Funding

Russian Ministry of Education and Science 1021062512064-0
6 · The paper itself

Abstract

This pilot study examined the long-term structural changes in the osteochondral unit of 20 patients with knee osteoarthritis (KOA) who underwent high tibial osteotomy (HTO) and received post-treatment with either platelet-rich plasma (PRP) or stromal vascular fraction (SVF). Ten patients were injected with autologous PRP (PRP subgroup), while another ten patients received autologous SVF (SVF subgroup) six weeks after surgery and were monitored for 18 months. Histological samples of bone and cartilage (2 mm in diameter and 2 cm long) were taken from tibial and femoral sites during surgery and 18-month post-HTO, and morphometric analyses were conducted using Mega-Morf12 software. Both post-treatment resulted in an increase in articular cartilage height at both sites (

Indexed as

corrective osteotomyknee osteoarthritismorphometryosteochondral unitplatelet-rich plasmastromal vascular fraction

Identifiers

PMID38791006
PMCPMC11118028

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.