Evidence map›Paper›PMID 38790959›Full record

ArticleBiomedicines2024

Influence of the Tissue Collection Procedure on the Adipogenic Differentiation of Human Stem Cells: Ischemic versus Well-Vascularized Adipose Tissue.

Pallabi Pal, Abelardo Medina, Sheetal Chowdhury, Courtney A Cates, Ratna Bollavarapu, Jon M Person, Benjamin McIntyre, Joshua S Speed, Amol V Janorkar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pallabi PalDepartment of Biomedical Materials Science, School of Dentistry, University of Mississippi Medical Center, 2500 N State Street, Jackson, MS 39216, USA.ORCID 0000-0003-0217-6029
Abelardo MedinaDivision of Plastic Surgery, Department of Surgery, University of Mississippi Medical Center, 2500 N State Street, Jackson, MS 39216, USA.
Sheetal ChowdhuryDepartment of Biomedical Materials Science, School of Dentistry, University of Mississippi Medical Center, 2500 N State Street, Jackson, MS 39216, USA.ORCID 0000-0002-0739-4183
Courtney A CatesDepartment of Biomedical Materials Science, School of Dentistry, University of Mississippi Medical Center, 2500 N State Street, Jackson, MS 39216, USA.
Ratna BollavarapuDepartment of Biomedical Materials Science, School of Dentistry, University of Mississippi Medical Center, 2500 N State Street, Jackson, MS 39216, USA.
Jon M PersonCancer Institute, University of Mississippi Medical Center, 2500 N State Street, Jackson, MS 39216, USA.
Benjamin McIntyreDivision of Plastic Surgery, Department of Surgery, University of Mississippi Medical Center, 2500 N State Street, Jackson, MS 39216, USA.
Joshua S SpeedDepartment of Physiology and Biophysics, University of Mississippi Medical Center, 2500 N State Street, Jackson, MS 39216, USA.
Amol V JanorkarDepartment of Biomedical Materials Science, School of Dentistry, University of Mississippi Medical Center, 2500 N State Street, Jackson, MS 39216, USA.

Funding

Tracking and Evaluation CoreU54GM115428 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI COMPRETTA, CAROLINE E. · 2016 to 2025
$38.2M
Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Babbette LaMarca, Jane F Reckelhoff · 2017 to 2026
$26.4M
The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI TAYLOR, ERIN BASSFORD · 2013 to 2022
$23.4M
Hypertension and Cardiorenal Research Training ProgramT32HL105324 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI Joey P. Granger · 2010 to 2026
$7.8M
Pilot Projects ProgramP30GM149404 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI DAVID E STEC · 2023 to 2026
$6.3M
Endothelin-1 in Obesity and Insulin ResistanceR01DK124327 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI SPEED, JOSHUA S · 2021 to 2025
$2.2M
3D Spheroid Model of Adipose PathophysiologyR01EB020006 · NIBIB · UNIVERSITY OF MISSISSIPPI MED CTR · PI JANORKAR, AMOL VIJAY · 2016 to 2019
$1.4M
NHLBI NIH HHS T32 HL105324NIBIB NIH HHS R01 EB020006NIBIB NIH HHS R01EB020006NIDDK NIH HHS R01 DK124327NIDDK NIH HHS R01DK124327NIGMS NIH HHS P20 GM104357NIGMS NIH HHS P20GM104357NIGMS NIH HHS P20 GM121334NIGMS NIH HHS P20GM121334NIGMS NIH HHS P30 GM149404NIGMS NIH HHS U54 GM115428
6 · The paper itself

Abstract

Clinical and basic science applications using adipose-derived stem cells (ADSCs) are gaining popularity. The current adipose tissue harvesting procedures introduce nonphysiological conditions, which may affect the overall performance of the isolated ADSCs. In this study, we elucidate the differences between ADSCs isolated from adipose tissues harvested within the first 5 min of the initial surgical incision (well-vascularized, nonpremedicated condition) versus those isolated from adipose tissues subjected to medications and deprived of blood supply during elective free flap procedures (ischemic condition). ADSCs isolated from well-vascularized and ischemic tissues positively immunostained for several standard stem cell markers. Interestingly, the percent change in the CD36 expression for ADSCs isolated from ischemic versus well-vascularized tissue was significantly lower in males than females (

Indexed as

3D spheroidadipose tissueCD36flow cytometrytriglyceride

Identifiers

PMID38790959
PMCPMC11117639

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.