ReviewBiomedicines2024
Pediatric Lower Urinary Tract Dysfunction: A Comprehensive Exploration of Clinical Implications and Diagnostic Strategies.
Review in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Hedgehog pathway disruption alters urothelial differentiation and continence mechanisms in the female mouse lower urinary tract.American journal of physiology. Renal physiology · 2026Article
- Severe Lower Urinary Tract Dysfunction in Otherwise Healthy Children: A Three-Case Series and Narrative Review.Pediatric reports · 2026Article
- Hypopressive physiotherapy for refractory non-neurogenic underactive bladder in children: a retrospective case series.Frontiers in pediatrics · 2026Article
- Indications, findings, and clinical impact of invasive pediatric urodynamic studies in Iraqi children.Frontiers in pediatrics · 2026Article
- Spinal cord injury-induced overflow incontinence reshapes the activin-follistatin-inhibin axis in mouse bladder and kidney.Frontiers in molecular biosciences · 2026Article
- Smooth muscle of the lower urinary tract: BK-RyR coupling in physiology and pathophysiology.Journal of muscle research and cell motility · 2025Review
- Lower Urinary Tract Symptoms in Patients with Congenital Genitourinary Anomalies.Current urology reports · 2025Review
- Adverse childhood experiences and lower urinary tract symptoms in adolescence: the mediating effect of inflammation.International journal of epidemiology · 2025Article
- Exploring dysfunctional voiding in girls: a comprehensive literature review of assessment and management strategies.BMC urology · 2025Review
- Pediatric Voiding Dysfunction: Definitions and Management.Medicina (Kaunas, Lithuania) · 2025Review
Corrections and comments
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Authors and funding
1 author.
Funding
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Abstract
Lower urinary tract dysfunction is clinically important because it may cause urinary tract infections, mainly due to accumulation of residual urine, and adversely affect renal function. In addition, it may cause urinary incontinence, strongly affecting the child's quality of life. The function of the lower urinary tract is closely associated with function of the bowel because constipation is commonly present with bladder dysfunction. The interplay between the lower urinary tract and bowel function, coupled with common conditions such as detrusor overactivity and voiding dysfunction, requires a nuanced diagnostic approach. Detrusor overactivity, a benign but socially harmful condition, is the principal cause of daytime urinary incontinence in childhood. It needs to be differentiated from more serious conditions such as neurogenic bladder dysfunction or urethral obstruction. Voiding dysfunction, a habitual sphincter contraction during voiding, is common in children with detrusor overactivity and may be self limiting but may also result in residual urine and urinary tract infections. It may resemble, in severe cases, neurogenic bladder dysfunction, most often caused by spinal dysraphism, which very often leads to recurrent urinary tract infections and high intravesical pressures, jeopardizing renal function. A voiding diary is crucial in the initial evaluation of lower urinary tract function in children.
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