Evidence map›Paper›PMID 38790721›Full record

ArticleAntioxidants (Basel, Switzerland)2024

Lutein and Zeaxanthin Enhance, Whereas Oxidation, Fructosylation, and Low pH Damage High-Density Lipoprotein Biological Functionality.

Jingyuan Zheng, Brian V Hong, Joanne K Agus, Xinyu Tang, Nola R Klebaner, Siyu Chen, Fei Guo, Danielle J Harvey, Carlito B Lebrilla, Angela M Zivkovic

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jingyuan ZhengDepartment of Nutrition, University of California Davis, Davis, CA 95616, USA.
Brian V HongDepartment of Nutrition, University of California Davis, Davis, CA 95616, USA.ORCID 0000-0001-7080-2744
Joanne K AgusDepartment of Nutrition, University of California Davis, Davis, CA 95616, USA.ORCID 0000-0002-6755-2702
Xinyu TangDepartment of Nutrition, University of California Davis, Davis, CA 95616, USA.ORCID 0000-0002-4567-4012
Nola R KlebanerDepartment of Nutrition, University of California Davis, Davis, CA 95616, USA.
Siyu ChenDepartment of Chemistry, University of California Davis, Davis, CA 95616, USA.ORCID 0009-0003-9584-6905
Fei GuoDepartment of Molecular and Cellular Biology, University of California Davis, Davis, CA 95616, USA.ORCID 0000-0003-4991-114X
Danielle J HarveyDepartment of Public Health Sciences, University of California Davis, Davis, CA 95616, USA.
Carlito B LebrillaDepartment of Chemistry, University of California Davis, Davis, CA 95616, USA.ORCID 0000-0001-7190-5323
Angela M ZivkovicDepartment of Nutrition, University of California Davis, Davis, CA 95616, USA.ORCID 0000-0002-2828-7862

Funding

Comprehensive Characterization of Glycosylation Alterations in Alzheimer’s DiseaseR01AG062240 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JIN, LEE-WAY, LEBRILLA, CARLITO B · 2018 to 2022
$3.3M
Development of a Novel Technology for Preparative Fractionation and Characterization of Lipoprotein ParticlesR01GM147545 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ZIVKOVIC, ANGELA M · 2022 to 2025
$1.2M
Novel Separation Methods for exRNA Carriers: Extracellular Vesicles, Lipoprotein Particles, and Protein AggregatesUH3CA241694 · NCI · JOHNS HOPKINS UNIVERSITY · PI WITWER, KENNETH W · 2021 to 2022
$1.1M
NCI NIH HHS UH3 CA241694NIA NIH HHS R01 AG062240NIGMS NIH HHS R01 GM147545NIH HHS R01AG062240NIH HHS R01GM147545NIH HHS UH3CA241694University of California, Davis Henry A. Jastro Award 2022
6 · The paper itself

Abstract

High-density lipoproteins (HDLs) are key regulators of cellular cholesterol homeostasis but are functionally altered in many chronic diseases. The factors that cause HDL functional loss in chronic disease are not fully understood. It is also unknown what roles antioxidant carotenoids play in protecting HDL against functional loss. The aim of this study was to measure how various disease-associated chemical factors including exposure to (1) Cu

Indexed as

carotenoidschronic inflammationHDLoxidative stress

Identifiers

PMID38790721
PMCPMC11118252

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.