Evidence map›Paper›PMID 38790704›Full record

ArticleAntioxidants (Basel, Switzerland)2024

The Antioxidant

Jingyi Qi, Shuaishuai Zhou, Guisheng Wang, Rongrong Hua, Xiaoping Wang, Jian He, Zi Wang, Yinhua Zhu, Junjie Luo, Wenbiao Shi and 2 more

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  10. Frontiers in nutrition · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jingyi QiKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Shuaishuai ZhouKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Guisheng WangDepartment of Radiology, The Third Medical Centre, Chinese PLA General Hospital, Beijing 100039, China.
Rongrong HuaDepartment of Radiology, The Third Medical Centre, Chinese PLA General Hospital, Beijing 100039, China.
Xiaoping WangZhejiang Medicine Co., Ltd., Shaoxing 312366, China.
Jian HeNational Center of Technology Innovation for Dairy, Hohhot 010110, China.
Zi WangKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Yinhua ZhuKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Junjie LuoKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-8987-0533
Wenbiao ShiKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.ORCID 0000-0001-7724-9582
Yongting LuoKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.ORCID 0000-0001-7834-8742
Xiaoxia ChenDepartment of Radiology, The Third Medical Centre, Chinese PLA General Hospital, Beijing 100039, China.

Funding

the National Key R&D Program of China 2022YFF1100405
6 · The paper itself

Abstract

backgroundThe discovery of traditional plants' medicinal and nutritional properties has opened up new avenues for developing pharmaceutical and dietary strategies to prevent atherosclerosis. However, the effect of the antioxidant PURPOSE: This study aims to investigate the inhibitory effect and the potential mechanism of DOP on high-fat diet-induced atherosclerosis in Apolipoprotein E knockout (ApoE STUDY DESIGN AND

methodsThe identification of DOP was measured by high-performance gel permeation chromatography (HPLC) and Fourier transform infrared spectroscopy (FTIR). We used high-fat diet (HFD)-induced atherosclerosis in ApoE

resultsDOP effectively inhibited histopathological deterioration in atherosclerotic mice and significantly reduced serum lipid levels, inflammatory factors, and malondialdehyde (F/B) production. Additionally, the levels of anti-inflammatory factors and the activity of antioxidant enzymes, including superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX), were significantly increased after DOP intervention. Furthermore, we found that DOP restructures the gut microbiota composition by decreasing the

conclusionsThis study suggests that DOP has the potential to be developed as a food prebiotic for the treatment of atherosclerosis in the future.

Indexed as

anti-inflammatoryantioxidantatherosclerosisDendrobium officinale polysaccharidegut microbiota

Identifiers

PMID38790704
PMCPMC11117934

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.