Evidence map›Paper›PMID 38790630›Full record

ArticleAntioxidants (Basel, Switzerland)2024

Luteolin Alleviates Cadmium-Induced Kidney Injury by Inhibiting Oxidative DNA Damage and Repairing Autophagic Flux Blockade in Chickens.

Kanglei Zhang, Jiahui Li, Wenxuan Dong, Qing Huang, Xueru Wang, Kai Deng, Waseem Ali, Ruilong Song, Hui Zou, Di Ran and 2 more

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. The role of SIRT1 in kidney diseases.International urology and nephrology · 2025
    Review
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kanglei ZhangCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Jiahui LiCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Wenxuan DongCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao 266000, China.
Qing HuangCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Xueru WangCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Kai DengCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Waseem AliCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Ruilong SongCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Hui ZouCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Di RanCollege of Veterinary Medicine, Southwest University, Chongqing 400715, China.
Gang LiuCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Zongping LiuCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0001-9071-8363

Funding

111 Project D18007National Key R&D Program of China 2023YFD1801100National Natural Science Foundation of China 32072923National Natural Science Foundation of China 32072933National Natural Science Foundation of China 32273086Postdoctoral Research Funding of Yangzhou University 137070430
6 · The paper itself

Abstract

Chickens are a major source of meat and eggs in human food and have significant economic value. Cadmium (Cd) is a common environmental pollutant that can contaminate feed and drinking water, leading to kidney injury in livestock and poultry, primarily by inducing the generation of free radicals. It is necessary to develop potential medicines to prevent and treat Cd-induced nephrotoxicity in poultry. Luteolin (Lut) is a natural flavonoid compound mainly extracted from peanut shells and has a variety of biological functions to defend against oxidative damage. In this study, we aimed to demonstrate whether Lut can alleviate kidney injury under Cd exposure and elucidate the underlying molecular mechanisms. Renal histopathology and cell morphology were observed. The indicators of renal function, oxidative stress, DNA damage and repair, NAD

Indexed as

autophagic fluxcadmiumluteolinPARP-1SIRT1

Identifiers

PMID38790630
PMCPMC11117664

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.