Evidence map›Paper›PMID 38790577›Full record

ReviewChildren (Basel, Switzerland)2024

A Comprehensive Look at the Development of Asthma in Children.

Ileana Diana Diaconu, Veronica Gheorman, Gabriela Adriana Grigorie, Cristian Gheonea, Tiberiu-Stefanita Tenea-Cojan, Beatrice Mahler, Ion Alexandru Voropanov, Mihnea Cristian Firoiu, Andreea Silvia Pîrvu, Alexandru Bogdan Popescu and 1 more

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ileana Diana DiaconuDepartment of Pediatric Pneumology, University of Medicine and Pharmacy of Craiova, Petru Rareș 2 Str., 200349 Craiova, Romania.ORCID 0000-0002-2439-2550
Veronica GheormanDepartment of Medical Semiology, University of Medicine and Pharmacy of Craiova, Petru Rareș 2 Str., 200349 Craiova, Romania.
Gabriela Adriana GrigorieDepartment of Pneumology, University of Medicine and Pharmacy of Craiova, Petru Rareș 2 Str., 200349 Craiova, Romania.
Cristian GheoneaDepartment of Pediatrics, University of Medicine and Pharmacy of Craiova, Petru Rareș 2 Str., 200349 Craiova, Romania.
Tiberiu-Stefanita Tenea-CojanDepartment of Surgery, University of Medicine and Pharmacy of Craiova, CFR Hospital of Craiova, Stirbei-Voda Str., 200374 Craiova, Romania.
Beatrice MahlerDepartment of Pneumology, Faculty of Medicine "Carol Davila", "Marius Nasta" Institute of Pneumoftiziology, 050159 Bucharest, Romania.
Ion Alexandru VoropanovDepartment of Pediatric Pneumology, Carol Davila University of Medicine and Pharmacy, "Marius Nasta" Institute of Pneumoftiziology, 050159 Bucharest, Romania.
Mihnea Cristian FiroiuDepartment of Urology, Fundeni Clinical Institute, Carol Davila University of Medicine and Pharmacy, Sos. Fundeni nr. 258, 022328 Bucharest, Romania.
Andreea Silvia PîrvuDepartment of Biochemistry, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Alexandru Bogdan PopescuRadiology Department, Targoviste County Emergency Hospital, Tudor Vladimirescu 48 Str., 130083 Targoviste, Romania.
Renata VăruțDepartment of Pharmacology, University of Medicine and Pharmacy, Petru Rareş Street 2-4, 200349 Craiova, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma, a prevalent chronic respiratory condition affecting millions of children globally, presents a significant health challenge. This review critically examines the developmental pathways of asthma in children, focusing on genetic, environmental, and early-life determinants. Specifically, we explore the impact of prenatal and postnatal factors such as maternal smoking, nutrition, respiratory infections, and allergen exposure on asthma development. Our analysis highlights the intricate interplay of these influences and their contribution to childhood asthma. Moreover, we emphasize targeted strategies and interventions to mitigate its burden, including genetic counseling for at-risk families, environmental modifications to reduce triggers, and early-life immunomodulation. By delving into these preventive measures and interventions, our review aims to provide actionable insights for healthcare professionals in developing tailored strategies to address the complexities of childhood asthma. In summary, this article offers a detailed examination of asthma development in children, aiming to enhance understanding and inform efforts to reduce its burden through targeted interventions.

Indexed as

allergen exposurechildhood asthmaearly-life influencesenvironmental factorsgenetic predispositionimmunomodulationmaternal smokingprenatal carepreventive measuresrespiratory health

Identifiers

PMID38790577
PMCPMC11120211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.