Evidence map›Paper›PMID 38790342›Full record

ArticleBioengineering (Basel, Switzerland)2024

Relative Fundamental Frequency: Only for Hyperfunctional Voices? A Pilot Study.

Sol Ferrán, Carla Rodríguez-Zanetti, Octavio Garaycochea, David Terrasa, Carlos Prieto-Matos, Beatriz Del Río, Maria Pilar Alzuguren, Secundino Fernández

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Normative Thresholds for Acoustic Estimates of Relative Fundamental Frequency.Journal of voice : official journal of the Voice Foundation · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sol FerránClínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0003-2266-816X
Carla Rodríguez-ZanettiClínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0009-0000-6545-5565
Octavio GaraycocheaClínica Universidad de Navarra, 31008 Pamplona, Spain.
David TerrasaClínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0001-8671-1281
Carlos Prieto-MatosClínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-0292-8828
Beatriz Del RíoClínica Universidad de Navarra, 31008 Pamplona, Spain.
Maria Pilar AlzugurenMedical Engineering Laboratory, School of Medicine, Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-2144-3404
Secundino FernándezClínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-3858-0034

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Assessing phonatory disorders due to laryngeal biomechanical alterations requires aerodynamic analysis, assessing subglottic pressure, transglottic flow, and laryngeal resistance. This study explores whether the acoustic parameter, the relative fundamental frequency (RFF), can be studied using the current acoustic analysis protocol at the University of Navarra's voice laboratory and its association with pathologies linked to laryngeal biomechanical alterations. (2) Methods: A retrospective cohort study included patients diagnosed with muscular tension dysphonia, organic lesions of the vocal fold, and vocal fold paralysis (VFP) at the Clínica Universidad de Navarra from 2019 to 2021. Each patient underwent endoscopic laryngeal exploration, followed by acoustic study, RFF calculation, and an aerodynamic study. Additionally, a control group was recruited. (3) Results: 79 patients and 22 controls were studied. Two-way ANOVA showed significant effects for groups and cycles in offset and onset cycles. Statistically significant differences were observed in cycle 1 onset among all groups and in cycles 1 and 2 between the control group and non-healthy groups. (4) Conclusions: RFF is a valuable indicator of phonatory biomechanics, distinguishing healthy and pathological voices and different disorders. RFF in onset cycles offers a cost-effective, accurate method for assessing biomechanical disorders without complex aerodynamic analyses. This study describes RFF values in VFP for the first time, revealing differences regardless of aerodynamic patterns.

Indexed as

muscle tension dysphoniarelative fundamental frequencyvocal hyperfunctionvocal offsetvocal onsetvoice acoustics

Identifiers

PMID38790342
PMCPMC11117970

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.