SynthesisRespiratory research2024
Rates of bronchopulmonary dysplasia in very low birth weight neonates: a systematic review and meta-analysis.
Synthesis in Respiratory research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Intratracheal instillation of corticosteroids combined with surfactant for preventing chronic lung disease in preterm infants.The Cochrane database of systematic reviews · 2025Pooled it
- Clinical and Imaging Data-based Machine Learning for Early Diagnosis of Bronchopulmonary Dysplasia: A Meta-analysis.Current medical imaging · 2025Pooled it
- Improving early risk stratification for bronchopulmonary Dysplasia in preterm infants using machine learning: development and external validation.Annals of medicine · 2026Article
- Burden and predictors of bronchopulmonary dysplasia in preterm infants: A seven-year cohort.Journal of Taibah University Medical Sciences · 2026Article
- Pattern and Predictors of Bronchopulmonary Dysplasia in Preterm Infants in New South Wales, Australia: A Population-Based Cohort Study.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Does more granular data equal better bronchopulmonary dysplasia prediction?Pediatric research · 2026Article
- Cystic lung lesions secondary to persistent pulmonary interstitial emphysema in preterm infants: imaging features and clinical course.Pediatric radiology · 2026Article
- Mortality and morbidity in very preterm infants in Switzerland spanning 16 years (2006-2021).BMJ paediatrics open · 2026Article
- Left ventricular diastolic dysfunction in preterm infants with bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Observational
- Expression and significance of miR-9-5p and GCH1 in neonates with bronchopulmonary dysplasia.Translational pediatrics · 2026Article
- BronQ Family: assessing the long-term impact of Bronchopulmonary Dysplasia on affected families' health-related quality of life - protocol of a multi-country study.BMJ paediatrics open · 2026Article
- Flavin adenine dinucleotide increases antioxidant availability and protects neonatal C57Bl6 lungs from high oxygen induced lung injury.American journal of physiology. Cell physiology · 2026Article
- A nomogram to predict bronchopulmonary dysplasia in very preterm and/or very low birth weight infants with early-onset sepsis.BMC pediatrics · 2026Observational
- Early prediction of bronchopulmonary dysplasia by urinary metabolomics: a case-control study.Thorax · 2026Observational
- Development and internal validation of a clinical nomogram for predicting bronchopulmonary dysplasia in preterm infants.Experimental and therapeutic medicine · 2026Article
- Common Biomarkers in Chronic Obstructive Pulmonary Disease and Bronchopulmonary Dysplasia: A Narrative Review of an Intriguing Interplay.International journal of molecular sciences · 2026Review
- Association of birth weight Z-score with bronchopulmonary dysplasia or mortality in very preterm infants: a cohort study.BMJ open respiratory research · 2026Article
- Integration of miRNA profiles and clinical data for early risk assessment of bronchopulmonary dysplasia in VLBW and ELBW newborn infants: a discovery study.Frontiers in pediatrics · 2026Article
- Preterm birth, bronchopulmonary dysplasia and the risk of allergic diseases.Pediatric research · 2026Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
importanceLarge-scale estimates of bronchopulmonary dysplasia (BPD) are warranted for adequate prevention and treatment. However, systematic approaches to ascertain rates of BPD are lacking.
objectiveTo conduct a systematic review and meta-analysis to assess the prevalence of BPD in very low birth weight (≤ 1,500 g) or very low gestational age (< 32 weeks) neonates. DATA SOURCES: A search of MEDLINE from January 1990 until September 2019 using search terms related to BPD and prevalence was performed. STUDY SELECTION: Randomized controlled trials and observational studies evaluating rates of BPD in very low birth weight or very low gestational age infants were eligible. Included studies defined BPD as positive pressure ventilation or oxygen requirement at 28 days (BPD28) or at 36 weeks postmenstrual age (BPD36). DATA EXTRACTION AND SYNTHESIS: Two reviewers independently conducted all stages of the review. Random-effects meta-analysis was used to calculate the pooled prevalence. Subgroup analyses included gestational age group, birth weight group, setting, study period, continent, and gross domestic product. Sensitivity analyses were performed to reduce study heterogeneity. MAIN OUTCOMES AND MEASURES: Prevalence of BPD defined as BPD28, BPD36, and by subgroups.
resultsA total of 105 articles or databases and 780,936 patients were included in this review. The pooled prevalence was 35% (95% CI, 28-42%) for BPD28 (n = 26 datasets, 132,247 neonates), and 21% (95% CI, 19-24%) for BPD36 (n = 70 studies, 672,769 neonates). In subgroup meta-analyses, birth weight category, gestational age category, and continent were strong drivers of the pooled prevalence of BPD. CONCLUSIONS AND RELEVANCE: This study provides a global estimation of BPD prevalence in very low birth weight/low gestation neonates.
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