Evidence map›Paper›PMID 38789881›Full record

ReviewJournal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology2024

Cellular therapies for bone repair: current insights.

Paul Rodham, Farihah Khaliq, Vasileos Giannoudis, Peter V Giannoudis

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Writing for JOOT: raising standards in clinical research and evidence synthesis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paul RodhamAcademic Department of Trauma and Orthopaedics, School of Medicine, University of Leeds, Leeds, UK.
Farihah KhaliqAcademic Department of Trauma and Orthopaedic Surgery, School of Medicine, University of Leeds, Leeds, UK.
Vasileos GiannoudisAcademic Department of Trauma and Orthopaedics, School of Medicine, University of Leeds, Leeds, UK.
Peter V GiannoudisAcademic Department of Trauma and Orthopaedics, School of Medicine, University of Leeds, Leeds, UK. pgiannoudi@aol.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells are core to bone homeostasis and repair. They both provide the progenitor cells from which bone cells are formed and regulate the local cytokine environment to create a pro-osteogenic environment. Dysregulation of these cells is often seen in orthopaedic pathology and can be manipulated by the physician treating the patient. This narrative review aims to describe the common applications of cell therapies to bone healing whilst also suggesting the future direction of these techniques.

Indexed as

Cell- and Tissue-Based TherapyMesenchymal Stem Cell TransplantationBone RegenerationFracture HealingHumansMesenchymal Stem CellsOsteogenesisCellular therapyClinical applicationsFracture healingStem cells

Identifiers

PMID38789881
PMCPMC11132192

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.