ArticlePain and therapy2024
Correlations of The Central Sensitization Inventory, conditioned pain modulation, cognitions and psychological factors in individuals with chronic neck pain: A cross-sectional study.
Article in Pain and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of transcranial direct current stimulation on pain and function in patients with knee osteoarthritis: A systematic review and meta-analysis.PM & R : the journal of injury, function, and rehabilitation · 2026Pooled it
- The relationship between neck and body awareness, pain, and proprioception with central sensitization in patients with chronic nonspecific neck pain.BMC musculoskeletal disorders · 2026Trial
- Pain Science Education, Stress Management, and Cognition-Targeted Exercise Therapy in Chronic Whiplash Disorders: A Randomized Clinical Trial.JAMA network open · 2025Trial
- A Randomized, Double-Blind, Parallel-Controlled Trial: Addressing Kinesiophobia in Post-Meniscoplasty Patients Through Progressive Muscle Relaxation Training and Acupressure.Pain research & management · 2025Trial
- Conditioned Pain Modulation and Pleasant Pain Relief as Complementary Processes Reflecting Individual Differences in Pain Coping: A Clustering Approach.European journal of pain (London, England) · 2026Article
- Multidimensional Analysis of Physical, Psychosocial, and Cognitive Impairment in People with Chronic Neck Pain.Medicina (Kaunas, Lithuania) · 2026Article
- Evaluation of kinesiophobia, central sensitization, and related factors in patients with gout: a cross-sectional study.Clinical rheumatology · 2026Article
- Association between lifestyle habits and central sensitization in community-dwelling older adults in Japan: a cross-sectional analysis from the Otassha study.BMC geriatrics · 2026Article
- A review of the synergistic mechanisms of Yijinjing, meridian sinew therapy, dry needling, and Fascial Manipulation in chronic cervical myofascial pain based on the fascia-meridian sinew continuum.Frontiers in medicine · 2026Review
- Evaluation of the presence of neuropathic pain and/or central sensitization in patients with radiographic axial spondyloarthritis followed at a tertiary hospital.Advances in rheumatology (London, England) · 2025Observational
- Opioid Stewardship and Gastrointestinal (GI)-Sparing Alternatives in Primary Care Pain Management.Cureus · 2025Review
- Identifying potential action points for reducing kinesiophobia among atrial fibrillation patients: a network and DAG analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Quantitative sensory testing for pain: What exactly are we measuring?Current opinion in psychology · 2025Review
- Conditioned Pain Modulation in Patients with Hemophilic Arthropathy: A Cross-Sectional Cohort Study.Journal of clinical medicine · 2025Article
- Current and future advances in practice: cervical spondylosis and mechanical neck pain.Rheumatology advances in practice · 2025Review
- Clinical features, risk factors, and a nomogram for predicting refractory cervicogenic headache: a retrospective multivariate analysis.Frontiers in neurology · 2025Article
- Cross-Cultural Adaptation and Validation of the Central Sensitization Inventory Among Chinese Patients with Chronic Non-Specific Low Back Pain.Journal of pain research · 2024Article
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Authors and funding
5 authors.
Funding
Abstract
introductionChronic neck pain (CNP) is a global public health problem, with high prevalence and absenteeism rates. Central sensitization (CS) as a basis for chronic pain may play an essential role in its development and progression. It is often comorbid with low conditioned pain modulation (CPM) effects, cognitions, and psychological problems.
objectivesThe purposes of this study were to (1) explore the relationship between pain-related cognitions and psychological factors, CPM effects, and the central sensitization inventory (CSI) scores; and (2) determine whether cognitions and psychological factors can predict CSI scores and CPM effects in individuals with CNP.
methodsFifty-four individuals with CNP were recruited for this cross-sectional study. The following outcome measures were evaluated: The CSI (screening tool) was compared with the cold pressor test (CPT), which was the psychophysical test used to assess the CPM; neck pain intensity using the visual analogue scale (VAS), as well as pain-related cognitions (including kinesiophobia and pain catastrophization) and psychological states (including anxiety and depression) using self-report questionnaires.
resultsCSI score was not associated with the CPM effect (r = 0.257, p > 0.05), and no cognitions or psychological factors were associated with CPM (p > 0.05), but CSI score was moderately positively correlated with kinesiophobia (r = 0.554, p < 0.01), lowly positively correlated with pain catastrophization (r = 0.332, p = 0.017) and anxiety (r = 0.492, p < 0.01), but not depression (r = 0.207, p = 0.132). Multiple linear regression analysis showed that kinesiophobia (B = 1.308, p < 0.01) and anxiety (B = 1.806, p = 0.02) were significant positive predictors of CSI score.
conclusionsThe findings confirm some of our hypotheses. Accordingly, the findings inferred that the CSI does not seem to respond to CPM effect in patients with CNP effectively. In addition, CSI score was associated with cognitions and psychological factors, of which kinesiophobia and anxiety were effective predictors. In clinical practice, pain-related cognitions and psychological factors should be fully considered to manage neck pain efficiently.
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