SynthesisNature communications2024
Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes.
Abstract readMeta-Analysis
In one paragraph
Synthesis in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes.Nature communications · 2024Pooled it
- Genomic, phenomic and geographic associations of leukocyte telomere length in the United States.Nature genetics · 2026Article
- Blood pressure, plasma proteins, and cardiovascular diseases: a network Mendelian randomization and observational study.European heart journal · 2026Observational
- Integration of multi-omics quantitative trait loci evidence reveals novel susceptibility genes for Alzheimer's disease.Scientific reports · 2025Article
- Bidirectional Two-Sample Mendelian Randomization Study Reveals Causal Associations Between Aging and Endometriosis.International journal of women's health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
101 authors.
Rebecca KeenerDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.ORCID http://orcid.org/0000-0001-9031-6866
Surya B ChhetriDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.
Carla J ConnellyDepartment of Molecular Biology and Genetics, Johns Hopkins University, Baltimore, MD, USA.
Margaret A TaubDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Matthew P ConomosDepartment of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-9744-0851
Joshua WeinstockDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.ORCID http://orcid.org/0000-0001-7013-1899
Bohan NiDepartment of Computer Science, Johns Hopkins University, Baltimore, MD, USA.
Benjamin StroberDepartment of Epidemiology, Harvard School of Public Health, Boston, MA, USA.ORCID http://orcid.org/0000-0003-2969-2808
Stella AslibekyanUniversity of Alabama at Birmingham, Birmingham, AL, USA.
Paul L AuerDivision of Biostatistics, Institute for Health & Equity, and Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID http://orcid.org/0000-0003-1735-8044
Lucas BarwickLTRC Data Coordinating Center, The Emmes Company, LLC, Rockville, MD, USA.
Lewis C BeckerGeneSTAR Research Program, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
John BlangeroDepartment of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.ORCID http://orcid.org/0000-0001-6250-5723
Eugene R BleeckerDepartment of Medicine, Division of Genetics, Genomics and Precision Medicine, University of Arizona, Tucson, AZ, USA.
Jennifer A BrodyCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-8509-148X
Brian E CadeChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0003-1424-0673
Juan C CeledonDivision of Pediatric Pulmonary Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0002-6139-5320
Yi-Cheng ChangDepartment of Internal Medicine, National Taiwan University, Taipei, Taiwan.
L Adrienne CupplesDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0273-7965
Brian CusterVitalant Research Institute, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-6251-366X
Barry I FreedmanInternal Medicine - Nephrology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.ORCID http://orcid.org/0000-0003-0275-5530
Mark T GladwinSchool of Medicine, University of Maryland, Baltimore, MD, USA.ORCID http://orcid.org/0000-0001-7267-9006
Susan R HeckbertDepartment of Epidemiology, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-7100-512X
Lifang HouDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Marguerite R IrvinDepartment of Epidemiology, University of Alabama Birmingham, Birmingham, AL, USA.
Carmen R IsasiDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Jill M JohnsenDepartment of Medicine and Institute for Stem Cell & Regenerative Medicine, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-2279-2550
Eimear E KennyThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Charles KooperbergDivision of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-7986-8560
Ryan L MinsterDepartment of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0001-7382-6717
Take NaseriNaseri & Associates Public Health Consultancy Firm and Family Health Clinic, Apia, Samoa.
Satupa'itea VialiOceania University of Medicine, Apia, Samoa.
Sergei NekhaiCenter for Sickle Cell Disease and Department of Medicine, College of Medicine, Howard University, Washington DC, USA.ORCID http://orcid.org/0000-0003-0744-7887
Nathan PankratzDepartment of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.ORCID http://orcid.org/0000-0001-5958-693X
Patricia A PeyserDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-9717-8459
Kent D TaylorThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Marilyn J TelenDepartment of Medicine, Duke University Medical Center, Durham, NC, USA.ORCID http://orcid.org/0000-0003-3809-1780
Baojun WuCenter for Individualized and Genomic Medicine Research (CIGMA), Department of Internal Medicine, Henry Ford Health System, Detroit, MI, USA.
Lisa R YanekDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0001-7117-1075
Ivana V YangDepartments of Biomedical Informatics, Medicine, and Epidemiology, University of Colorado, Boulder, CO, USA.
Christine AlbertHarvard Medical School, Boston, MA, USA.
Donna K ArnettDepartment of Epidemiology and Biostatistics, University of South Carolina, Columbia, SC, USA.
Allison E Ashley-KochDepartment of Medicine, Duke University Medical Center, Durham, NC, USA.ORCID http://orcid.org/0000-0001-5409-9155
Kathleen C BarnesDepartment of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Joshua C BisCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-3409-1110
Thomas W BlackwellDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Eric BoerwinkleHuman Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
Esteban G BurchardDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-7475-2035
April P CarsonDepartment of Medicine, University of Mississippi Medical Center, Jackson, MI, USA.ORCID http://orcid.org/0000-0002-7970-6756
Zhanghua ChenDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA.
Yii-Der Ida ChenThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.ORCID http://orcid.org/0000-0003-1741-3517
Dawood DarbarDivision of Cardiology, University of Illinois at Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-4103-5977
Mariza de AndradeDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA.
Patrick T EllinorCardiovascular Disease Initiative, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-2067-0533
Myriam FornageInstitute of Molecular Medicine, McGovern Medical School, the University of Texas Health Science Center at Houston, Houston, TX, USA.ORCID http://orcid.org/0000-0003-0677-8158
Bruce D GelbMindich Child Health and Development Institute and Departments of Pediatrics and Genetics and Genomic Sciences, Icahn School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0001-8527-5027
Frank D GillilandDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-9033-7269
Jiang HeDepartment of Medicine, Tulane University School of Medicine, New Orleans, LA, USA.
Talat IslamDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA.
Stefan KaabDepartment of Cardiology, University Hospital, LMU Munich, Munich, Germany.ORCID http://orcid.org/0000-0001-8824-3581
Sharon L R KardiaDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Shannon KellyVitalant Research Institute, San Francisco, CA, USA.
Barbara A KonkleDepartment of Medicine, University of Washington, Seattle, WA, USA.
Rajesh KumarNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.
Ruth J F LoosThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0001-8312-1438
Fernando D MartinezAsthma & Airway Disease Research Center, University of Arizona, Tucson, AZ, USA.
Stephen T McGarveyDepartment of Epidemiology & International Health Institute, Brown University School of Public Health, Providence, RI, USA.ORCID http://orcid.org/0000-0003-1233-6970
Deborah A MeyersDepartment of Medicine, Division of Genetics, Genomics and Precision Medicine, University of Arizona, Tucson, AZ, USA.
Braxton D MitchellDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0003-4920-4744
Courtney G MontgomeryGenes and Human Disease, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.ORCID http://orcid.org/0000-0002-9606-3772
Kari E NorthDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0002-8903-0366
Nicholette D PalmerDepartment of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA.ORCID http://orcid.org/0000-0001-8883-2511
Juan M PeraltaDepartment of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.ORCID http://orcid.org/0000-0002-8811-5579
Benjamin A RabyDivision of Pulmonary and Critical Care, Brigham and Women's Hospital, Boston, MA, USA.
Susan RedlineChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-6585-1610
Stephen S RichCenter for Public Health Genomics, Department of Public Health Sciences, University of Virginia, Charlottesville, VA, USA.ORCID http://orcid.org/0000-0003-3872-7793
Dan RodenDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.ORCID http://orcid.org/0000-0002-6302-0389
Jerome I RotterThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.ORCID http://orcid.org/0000-0001-7191-1723
Ingo RuczinskiDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
David SchwartzDepartments of Medicine and Immunology, University of Colorado, Boulder, CO, USA.
Frank SciurbaDivision of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
M Benjamin ShoemakerDepartments of Medicine, Pharmacology, and Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
Edwin K SilvermanChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Moritz F SinnerDepartment of Cardiology, University Hospital, LMU Munich, Munich, Germany.ORCID http://orcid.org/0000-0002-6660-796X
Nicholas L SmithDepartment of Medicine, Tulane University School of Medicine, New Orleans, LA, USA.ORCID http://orcid.org/0000-0003-3483-353X
Albert V SmithDepartment of Biostatistics, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0003-1942-5845
Hemant K TiwariDepartment of Biostatistics, University of Alabama Birmingham, Birmingham, AL, USA.
Ramachandran S VasanDepartment of Medicine, Boston University School of Medicine, Boston, MA, USA.ORCID http://orcid.org/0000-0001-7357-5970
Scott T WeissChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0001-7196-303X
L Keoki WilliamsCenter for Individualized and Genomic Medicine Research (CIGMA), Department of Internal Medicine, Henry Ford Health System, Detroit, MI, USA.
Yingze ZhangDivision of Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0001-6947-2901
Elad ZivDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-2324-2884
Laura M RaffieldDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0002-7892-193X
Alexander P ReinerDivision of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-1427-4470
NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium
TOPMed Hematology and Hemostasis Working Group
TOPMed Structural Variation Working Group
Marios ArvanitisDepartment of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD, USA.
Carol W GreiderDepartment of Molecular Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA, USA.ORCID http://orcid.org/0000-0002-5494-8126
Rasika A MathiasDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. rmathias@jhmi.edu.ORCID http://orcid.org/0000-0002-2282-9042
Alexis BattleDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA. ajbattle@jhu.edu.ORCID http://orcid.org/0000-0002-5287-627X
Funding
Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Joseph Leo Wiemels · 1996 to 2026
$46.4MChildhood Asthma in Urban Settings Leadership Center Administrative Supplement for URECA Yr4UM1AI160040 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI James E. Gern, DANIEL J JACKSON · 2021 to 2026
$41.1MSleep Disorders in Adults with Sickle Cell Disease: Frequency, Associations with Cardiovascular and Pain Indicators, and Responses to TreatmentU54MD007597 · NIMHD · HOWARD UNIVERSITY · PI William M. Southerland · 2019 to 2026
$37.7MZINC AND CA EDTA THERAPY OF PLUMBISMM01RR000052 · NCRR · JOHNS HOPKINS UNIVERSITY · PI BELCHER, HAROLYN MILLICENT EDITH · 1985 to 2007
$37.3MUrban Air Pollution and Children's Respiratory HealthP01ES011627 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AVOL, EDWARD · 2002 to 2011
$30.2MUniversity of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9MIDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVALR01HL092577 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2009 to 2025
$20.6MUSC Tobacco Center of Regulatory Science (TCORS) for Vulnerable PopulationsP50CA180905 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PENTZ, MARY ANN, SAMET, JONATHAN M · 2013 to 2017
$20.1MGenotypic Determinants of Aspirin Response in High Risk FamiliesU01HL072518 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BECKER, LEWIS C · 2002 to 2008
$12.8MTargeting early events in MUC5B-driven lung injury and fibrosisP01HL162607 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI David Albert Schwartz · 2023 to 2026
$12.4MTherapeutic target discovery in ADSP data via comprehensive whole-genome analysis incorporating ethnic diversity and systems approachesU01AG058589 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BOERWINKLE, ERIC A., DE JAGER, PHILIP L · 2018 to 2022
$11.1MClinical Genetics and Screening for Pulmonary FibrosisR01HL130974 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GARY MATTHEW HUNNINGHAKE, Benjamin Alexander Raby · 2016 to 2026
$10.0MBLRD VA I01 BX005295NCI NIH HHS P50 CA180905NCI NIH HHS R35 CA209974NCRR NIH HHS M01 RR000052NHGRI NIH HHS R01 HG010297NHLBI NIH HHS HHSN268201800001CNHLBI NIH HHS P01 HL162607NHLBI NIH HHS R01 HL061768NHLBI NIH HHS R01 HL068959NHLBI NIH HHS R01 HL076647NHLBI NIH HHS R01 HL079915NHLBI NIH HHS R01 HL087680NHLBI NIH HHS R01 HL087681NHLBI NIH HHS R01 HL087698NHLBI NIH HHS R01 HL092577NHLBI NIH HHS R01 HL105756NHLBI NIH HHS R01 HL112064NHLBI NIH HHS R01 HL120393NHLBI NIH HHS R01 HL130974NHLBI NIH HHS R01 HL139731NHLBI NIH HHS R01 HL143818NHLBI NIH HHS R01 HL149836NHLBI NIH HHS R01 HL153805NHLBI NIH HHS R01 HL157635NHLBI NIH HHS R01 HL158668NHLBI NIH HHS R35 HL135818NHLBI NIH HHS RC2 HL101651NHLBI NIH HHS U01 HL072518NHLBI NIH HHS U01 HL137162NHLBI NIH HHS U01 HL153009NHLBI NIH HHS UG1 HL139125NHLBI NIH HHS UG3 HL151865NIAID NIH HHS R01 AI132476NIAID NIH HHS R01 AI153239NIAID NIH HHS U01 AI160018NIAID NIH HHS UM1 AI160040NIA NIH HHS P30 AG028747NIA NIH HHS R01 AG058921NIA NIH HHS R01 AG069120NIA NIH HHS R01 AG081244NIA NIH HHS U01 AG052409NIA NIH HHS U01 AG058589NIDDK NIH HHS R01 DK071891NIDDK NIH HHS R01 DK107786NIEHS NIH HHS P01 ES009581NIEHS NIH HHS P01 ES011627NIEHS NIH HHS P01 ES022845NIEHS NIH HHS P30 ES007048NIEHS NIH HHS R00 ES027870NIEHS NIH HHS R01 ES016535NIEHS NIH HHS R01 ES021801NIEHS NIH HHS R01 ES023262NIEHS NIH HHS R03 ES014046NIGMS NIH HHS K12 GM123914NIGMS NIH HHS R01 GM152471NIGMS NIH HHS R35 GM139580NIMHD NIH HHS U54 MD007597U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL079915U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL105756U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL68959U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL87681U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) 5K12GM123914U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R01AG069120U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R01AG081244U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R01HL-120393U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R01HL153805U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R35CA209974U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R35GM139580
Abstract
Genome-wide association studies (GWAS) have become well-powered to detect loci associated with telomere length. However, no prior work has validated genes nominated by GWAS to examine their role in telomere length regulation. We conducted a multi-ancestry meta-analysis of 211,369 individuals and identified five novel association signals. Enrichment analyses of chromatin state and cell-type heritability suggested that blood/immune cells are the most relevant cell type to examine telomere length association signals. We validated specific GWAS associations by overexpressing KBTBD6 or POP5 and demonstrated that both lengthened telomeres. CRISPR/Cas9 deletion of the predicted causal regions in K562 blood cells reduced expression of these genes, demonstrating that these loci are related to transcriptional regulation of KBTBD6 and POP5. Our results demonstrate the utility of telomere length GWAS in the identification of telomere length regulation mechanisms and validate KBTBD6 and POP5 as genes affecting telomere length regulation.
Indexed as
Genome-Wide Association StudyTelomereTelomere HomeostasisCRISPR-Cas SystemsGene Expression RegulationHumansK562 CellsPolymorphism, Single Nucleotide
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