Evidence map›Paper›PMID 38789066›Full record

ReviewJournal of the American College of Radiology : JACR2024

Establishing a Validation Infrastructure for Imaging-Based Artificial Intelligence Algorithms Before Clinical Implementation.

Ojas A Ramwala, Kathryn P Lowry, Nathan M Cross, William Hsu, Christopher C Austin, Sean D Mooney, Christoph I Lee

Abstract readReview
In one paragraph

Review in Journal of the American College of Radiology : JACR, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ojas A RamwalaDepartment of Biomedical Informatics and Medical Education, University of Washington School of Medicine, Seattle, Washington.
Kathryn P LowryDepartment of Radiology, University of Washington School of Medicine, Seattle, Washington.
Nathan M CrossVice Chair of Informatics, Department of Radiology, University of Washington School of Medicine, Seattle, Washington.
William HsuDepartment of Radiological Sciences, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, California; Department of Bioengineering, University of California, Los Angeles, Samueli School of Engineering, Los Angeles, California; Deputy Editor, Radiology: Artificial Intelligence.
Christopher C AustinGlobal Physician Lead, Clinical AI, DeepHealth, Somerville, Massachusetts.
Sean D MooneyDirector, Center for Information Technology, National Institutes of Health, Bethesda, Maryland.
Christoph I LeeDepartment of Radiology, University of Washington School of Medicine, Seattle, Washington; Department of Health Systems and Population Health, University of Washington School of Public Health, Seattle, Washington; Director, Northwest Screening and Cancer Outcomes Research Enterprise, University of Washington; Deputy Editor, JACR. Electronic address: stophlee@uw.edu.

Funding

Risk-based Imaging Strategies to Improve Breast Cancer Surveillance OutcomesP01CA154292 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KARLA M KERLIKOWSKE · 2011 to 2026
$52.9M
Artificial Intelligence for Improved Breast Cancer Screening Accuracy: External Validation, Refinement, and Clinical TranslationR37CA240403 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI CHRISTOPH I LEE · 2020 to 2026
$3.8M
Population-Based Evaluation of Artificial Intelligence for Mammography Priorto Widespread Clinical TranslationR01CA262023 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI CHRISTOPH I LEE · 2022 to 2026
$3.2M
NCI NIH HHS P01 CA154292NCI NIH HHS R01 CA262023NCI NIH HHS R37 CA240403
6 · The paper itself

Abstract

With promising artificial intelligence (AI) algorithms receiving FDA clearance, the potential impact of these models on clinical outcomes must be evaluated locally before their integration into routine workflows. Robust validation infrastructures are pivotal to inspecting the accuracy and generalizability of these deep learning algorithms to ensure both patient safety and health equity. Protected health information concerns, intellectual property rights, and diverse requirements of models impede the development of rigorous external validation infrastructures. The authors propose various suggestions for addressing the challenges associated with the development of efficient, customizable, and cost-effective infrastructures for the external validation of AI models at large medical centers and institutions. The authors present comprehensive steps to establish an AI inferencing infrastructure outside clinical systems to examine the local performance of AI algorithms before health practice or systemwide implementation and promote an evidence-based approach for adopting AI models that can enhance radiology workflows and improve patient outcomes.

Indexed as

AlgorithmsArtificial IntelligenceDiagnostic ImagingHumansUnited StatesWorkflowArtificial intelligenceclinical implementationdeep learningexternal validationradiologist workflow

Identifiers

PMID38789066
PMCPMC11486600

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.