Evidence map›Paper›PMID 38787383›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2024

Very low-density lipoprotein receptor mediates triglyceride-rich lipoprotein-induced oxidative stress and insulin resistance.

Tahar Hajri, Mohamed Gharib, Thomas Fungwe, Amosy M'Koma

Abstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tahar HajriDepartment of Nutritional Sciences, College of Nursing and Allied Health Sciences, Howard University, Washington, District of Columbia, United States.ORCID 0000-0003-3805-3717
Mohamed GharibAdventHealth Tampa, Tampa, Florida, United States.
Thomas FungweDepartment of Nutritional Sciences, College of Nursing and Allied Health Sciences, Howard University, Washington, District of Columbia, United States.
Amosy M'KomaAdventHealth Tampa, Tampa, Florida, United States.

Funding

Differentiating Ulcerative Colitis and Crohns Colitis Through Proteomic PatternsR21DK095186 · NIDDK · MEHARRY MEDICAL COLLEGE · PI M'KOMA, AMOSY EPHREIM · 2013 to 2014
$408k
NIDDK NIH HHS R21 DK095186
6 · The paper itself

Abstract

Obesity is associated with excess lipid deposition in nonadipose tissues, leading to increased oxidative stress and insulin resistance. Very low-density lipoprotein receptor (VLDLR), a member of the LDL receptor family, binds and increases the catabolism of triglyceride-rich lipoproteins. Although VLDLR is highly expressed in the heart, its role in obesity-associated oxidative stress and insulin resistance is unclear. Here, we used lean (wild type), genetically obese leptin-deficient (

Indexed as

Insulin ResistanceMice, KnockoutObesityOxidative StressReceptors, LDLSuperoxidesTriglyceridesAnimalsLeptinLipoproteins, VLDLMaleMiceMice, Inbred C57BLMice, ObeseMyocardiumMyocytes, CardiacLeptinLipoproteins, VLDLNADPH OxidasesReceptors, LDLSuperoxidesTriglyceridesVLDL receptorinsulin resistanceNADPH oxidaseoxidative stresstriglyceride-rich lipoproteinsVLDLR

Identifiers

PMID38787383
PMCPMC11901340

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.