Evidence map›Paper›PMID 38787314›Full record

ArticleChaos (Woodbury, N.Y.)2024

Annihilation dynamics during spiral defect chaos revealed by particle models.

Timothy J Tyree, Patrick Murphy, Wouter-Jan Rappel

Abstract read
In one paragraph

Article in Chaos (Woodbury, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Timothy J TyreeDepartment of Physics, University of California San Diego, San Diego, California 92093, USA.ORCID 0000-0003-0897-5083
Patrick MurphyDepartment of Mathematics and Statistics, San Jose State University, San Jose, California 95192, USA.ORCID 0000-0003-1321-8749
Wouter-Jan RappelDepartment of Physics, University of California San Diego, San Diego, California 92093, USA.ORCID 0000-0003-3833-7197

Funding

The Dynamics of Human Atrial FibrillationR01HL083359 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Sanjiv M Narayan · 2008 to 2026
$7.9M
Patient-Directed Computational Analysis of Atrial FibrillationR01HL122384 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WOUTER-JAN RAPPEL · 2015 to 2026
$5.3M
Machine Learning in Atrial FibrillationR01HL149134 · NHLBI · STANFORD UNIVERSITY · PI NARAYAN, SANJIV M · 2020 to 2024
$3.8M
Training Program in Quantitative Integrative BiologyT32GM127235 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HWA, TERENCE · 2018 to 2022
$1.3M
NHLBI NIH HHS R01 HL083359NHLBI NIH HHS R01 HL122384NHLBI NIH HHS R01 HL149134NIGMS NIH HHS T32 GM127235
6 · The paper itself

Abstract

Pair-annihilation events are ubiquitous in a variety of spatially extended systems and are often studied using computationally expensive simulations. Here, we develop an approach in which we simulate the pair-annihilation of spiral wave tips in cardiac models using a computationally efficient particle model. Spiral wave tips are represented as particles with dynamics governed by diffusive behavior and short-ranged attraction. The parameters for diffusion and attraction are obtained by comparing particle motion to the trajectories of spiral wave tips in cardiac models during spiral defect chaos. The particle model reproduces the annihilation rates of the cardiac models and can determine the statistics of spiral wave dynamics, including its mean termination time. We show that increasing the attraction coefficient sharply decreases the mean termination time, making it a possible target for pharmaceutical intervention.

Identifiers

PMID38787314
PMCPMC11141445

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.