Evidence map›Paper›PMID 38787308›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2024

History of Infertility and Risk of Colorectal Cancer.

Leslie V Farland, Kimberly E Lind, Denise J Roe, Nazmus Saquib, Howard D Strickler, Lihong Qi, Cynthia A Thomson, Holly R Harris

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leslie V FarlandDepartment of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona.ORCID 0000-0001-7455-8531
Kimberly E LindDepartment of Health Promotion Sciences, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona.ORCID 0000-0002-8850-1576
Denise J RoeDepartment of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona.ORCID 0000-0001-6989-6579
Nazmus SaquibCollege of Medicine, Sulaiman Al Rajhi University, Al Bukayriyah, Saudi Arabia.ORCID 0000-0002-2819-2839
Howard D StricklerDepartment of Epidemiology and Biostatistics, Albert Einstein College of Medicine, Bronx, New York.ORCID 0000-0001-6397-7466
Lihong QiDepartment of Public Health Sciences, School of Medicine, University of California, Davis, Davis, California.ORCID 0000-0002-9108-5390
Cynthia A ThomsonUniversity of Arizona Cancer Center, University of Arizona, Tucson, Arizona.ORCID 0000-0003-3645-7048
Holly R HarrisProgram in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, Washington.ORCID 0000-0002-2572-6727

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Gina M Dayton · 2002 to 2026
$84.9M
Infertility and Risk of Breast, Gynecologic, and Colorectal CancerR03HD102403 · NICHD · UNIVERSITY OF ARIZONA · PI FARLAND, LESLIE V · 2021 to 2022
$154k
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) HD102403NCI NIH HHS P30 CA093373NHLBI NIH HHS HHSN268201600001CNHLBI NIH HHS HHSN268201600002CNHLBI NIH HHS HHSN268201600003CNHLBI NIH HHS HHSN268201600004CNHLBI NIH HHS HHSN268201600018CNICHD NIH HHS R03 HD102403
6 · The paper itself

Abstract

backgroundThere has been limited prior research on the association between infertility and risk of colorectal cancer.

methodsData from postmenopausal women in the Women's Health Initiative were used to estimate the association between self-reported infertility (12 months of trying to get pregnant without achieving a pregnancy) and the risk of colorectal cancer using Cox proportional hazard models.

resultsNo association was observed between infertility and risk of postmenopausal colorectal cancer [RR, 0.97; 95% confidence interval (CI), 0.87-1.08], invasive colorectal cancer (RR, 0.99; 95% CI, 0.88-1.10), or colorectal cancer mortality (RR, 0.89; 95% CI, 0.71-1.12).

conclusionsInfertility was not found to be associated with colorectal cancer risk among postmenopausal women. Risk did not vary by specific infertility diagnoses. IMPACT: Infertility may not be associated with colorectal cancer risk.

Indexed as

Colorectal NeoplasmsAgedFemaleHumansInfertilityMiddle AgedPostmenopauseProportional Hazards ModelsRisk Factors

Identifiers

PMID38787308
PMCPMC11293956

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.