Evidence map›Paper›PMID 38787202›Full record

ReviewPathogens (Basel, Switzerland)2024

Group A Streptococcal Infections in Pediatric Age: Updates about a Re-Emerging Pathogen.

Giada Maria Di Pietro, Paola Marchisio, Pietro Bosi, Massimo Luca Castellazzi, Paul Lemieux

Abstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Rare emm6.10Microorganisms · 2025
    Article
  4. Resurgence of Group A Streptococcal Infections.Indian journal of pediatrics · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Molecular and Clinical Characterization of InvasivePathogens (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Giada Maria Di PietroPediatric Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0003-4935-8436
Paola MarchisioDepartment of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0002-5691-3920
Pietro BosiDepartment of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.
Massimo Luca CastellazziPediatric Emergency Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Paul LemieuxDepartment of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.

Funding

This work was (partially) funded by Italian Ministry of Health - Current research IRCCS Cà Granda Ospedale Maggiore Policlinico di Milano" in order to proceed with the invoice's payment none
6 · The paper itself

Abstract

Group A Streptococcus (GAS) presents a significant global health burden due to its diverse clinical manifestations ranging from mild infections to life-threatening invasive diseases. While historically stable, the incidence of GAS infections declined during the COVID-19 pandemic but resurged following the relaxation of preventive measures. Despite general responsiveness to β-lactam antibiotics, there remains an urgent need for a GAS vaccine due to its substantial global disease burden, particularly in low-resource settings. Vaccine development faces numerous challenges, including the extensive strain diversity, the lack of suitable animal models for testing, potential autoimmune complications, and the need for global distribution, while addressing socioeconomic disparities in vaccine access. Several vaccine candidates are in various stages of development, offering hope for effective prevention strategies in the future.

Indexed as

Streptococcal InfectionsStreptococcal VaccinesStreptococcus pyogenesAnti-Bacterial AgentsChildChild, PreschoolCommunicable Diseases, EmergingCOVID-19Global HealthHumansSARS-CoV-2Anti-Bacterial AgentsStreptococcal Vaccinesgroup A Streptococcus (GAS)invasive group A streptococcal infection (iGAS)pharyngitisStreptococcus pyogenesvaccines

Identifiers

PMID38787202
PMCPMC11124454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.