Evidence map›Paper›PMID 38787168›Full record

ArticleVeterinary sciences2024

Comparison of Xylazine and Lidocaine Infusion versus Medetomidine Continuous Rate Infusion during General Anesthesia with Isoflurane in Horses Undergoing Emergency Laparotomy.

Paola Straticò, Giulia Guerri, Lorenza Bandera, Gianluca Celani, Laura Di Nunzio, Lucio Petrizzi, Vincenzo Varasano

Abstract read
In one paragraph

Article in Veterinary sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paola StraticòDepartment of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy.ORCID 0000-0001-5482-2665
Giulia GuerriDepartment of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy.ORCID 0000-0002-3110-107X
Lorenza BanderaDepartment of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy.ORCID 0009-0000-8661-1344
Gianluca CelaniDepartment of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy.ORCID 0000-0001-6302-3910
Laura Di NunzioDepartment of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy.
Lucio PetrizziDepartment of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy.ORCID 0000-0001-7830-7545
Vincenzo VarasanoDepartment of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy.

Funding

Next Generation EU. Project Code: ECS00000041, Project Title: Innovation, digitalization, and sustainability for the diffused economy in Central Italy-VITALITY C43C22000380007
6 · The paper itself

Abstract

(1) The main goals of general anesthesia include pain management and a safe anesthetic protocol for smooth recovery. In this retrospective study, we compared two anesthetic protocols for general anesthesia with isoflurane during emergency laparotomy: sedation with xylazine and the intraoperative infusion of lidocaine (X group) versus medetomidine as a preoperative sedation and intraoperative infusion (M group). (2) The medical records of horses who underwent emergency laparotomies between 2016 and 2023 were reviewed. According to the anesthetic protocol, patients were allocated to the X or M groups. Data about the horse, signalment, history, and anesthetic variables were analyzed. (3) Group X had a significantly higher heart rate (HR), lower respiratory rate (RR) and mean and diastolic arterial pressure (MAP/DAP). A progressive increase in HR and RR was observed in both groups. Group X underwent a decrease in RR and an increase in DAP. In Group M, a decrease in MAP and DAP was observed. Group M exhibited a longer recovery time with similar recovery scores. Both protocols provided safe anesthesia for emergency laparotomy, with minor cardiovascular and respiratory depression. Minor respiratory depression was detected when xylazine was used, while recovery was longer with medetomidine.

Indexed as

general anesthesiahorselaparotomylidocaineα2-agonists

Identifiers

PMID38787168
PMCPMC11125707

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.