Evidence map›Paper›PMID 38787068›Full record

ArticleToxins2024

Mindfulness in Facilitating Pelvic Floor Botulinum Toxin Injection in Women with Chronic Pelvic Pain.

Jacqueline V Aredo, Hannah K Tandon, Samin Panahi, Vy T Phan, Rezvan Ameli, Barbara I Karp, Pamela Stratton

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jacqueline V AredoRehabilitation Medicine Department, Intramural Research Program, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0003-0559-3565
Hannah K TandonRehabilitation Medicine Department, Intramural Research Program, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.
Samin PanahiDepartment of Family Science, School of Public Health, University of Maryland, College Park, MD 20742, USA.
Vy T PhanRehabilitation Medicine Department, Intramural Research Program, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.
Rezvan AmeliNIMH Representative to the Clinical Center Pain and Palliative Care Service, National Institutes of Health, Bethesda, MD 20892, USA.
Barbara I KarpOffice of the Clinical Director, Intramural Research Program, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-4604-0142
Pamela StrattonOffice of the Clinical Director, Intramural Research Program, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

Funding

The effectiveness of Botulinum toxin on persistent pelvic pain in women with endometriosisZIANS003159 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI STRATTON, PAMELA · 2017 to 2025
$643k
Intramural Research Program, National Institutes of Health none
6 · The paper itself

Abstract

Botulinum toxin (BoNT) injection can safely be done as an office-based procedure, but can be painful itself, especially when injecting pelvic floor muscles to treat chronic pelvic pain (CPP). Mindfulness interventions may reduce procedure-associated acute anxiety and pain. We applied mindfulness techniques to increase the tolerability of office-based pelvic floor BoNT injections in women with CPP. Women enrolled in a clinical trial of BoNT for endometriosis-associated CPP were offered a brief, guided mindfulness session before and/or after transvaginal injection. Anxiety, pain, and dysphoria were rated on a 0-10 numerical rating scale (NRS) before and after each mindfulness session. Eight women underwent mindfulness sessions. Five participants had a session before and two after the transvaginal injection. One participant had two sessions: one before and one after separate injections. All six women completing a session prior to injection had at least moderate anxiety, which lessened after the mindfulness session (median NRS change: -3.3/10). All three women reporting injection-associated pain experienced less intense pain following the post-injection session (median NRS change: -3/10). Three women experiencing dysphoria improved after the session (median NRS change: -3/10). A brief, guided mindfulness session may lessen acute pain, anxiety, and dysphoria associated with office-based transvaginal BoNT injection.

Indexed as

Chronic PainMindfulnessPelvic FloorPelvic PainAdultAnxietyBotulinum ToxinsEndometriosisFemaleHumansMiddle AgedBotulinum Toxinsbotulinum toxinchronic pelvic paincomplementary medicinemindfulnessofficed-based procedures

Identifiers

PMID38787068
PMCPMC11126137

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.