Evidence map›Paper›PMID 38786960›Full record

ArticleJournal of cardiovascular development and disease2024

Clinical Features and Patient Outcomes in Infective Endocarditis with Surgical Indication: A Single-Centre Experience.

Fausto Pizzino, Umberto Paradossi, Giancarlo Trimarchi, Giovanni Benedetti, Federica Marchi, Sara Chiappino, Mattia Conti, Gianluca Di Bella, Michele Murzi, Silvia Di Sibio and 3 more

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Surgery inJournal of clinical medicine · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Body Weight's Role in Infective Endocarditis Surgery.Journal of cardiovascular development and disease · 2024
    Article
  14. Article
  15. Article
  16. The Usefulness of the CHAJournal of clinical medicine · 2024
    Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fausto PizzinoCardiology Unit, Heart Centre, Fondazione Gabriele Monasterio-Regione Toscana, 54100 Massa, Italy.ORCID 0000-0003-1053-8325
Umberto ParadossiCardiology Unit, Heart Centre, Fondazione Gabriele Monasterio-Regione Toscana, 54100 Massa, Italy.
Giancarlo TrimarchiDepartment of Clinical and Experimental Medicine, University of Messina, 98100 Messina, Italy.ORCID 0009-0008-9165-7732
Giovanni BenedettiCardiology Unit, Heart Centre, Fondazione Gabriele Monasterio-Regione Toscana, 54100 Massa, Italy.
Federica MarchiCardiology Unit, Heart Centre, Fondazione Gabriele Monasterio-Regione Toscana, 54100 Massa, Italy.
Sara ChiappinoCardiology Unit, Heart Centre, Fondazione Gabriele Monasterio-Regione Toscana, 54100 Massa, Italy.
Mattia ContiDepartment of Surgical Molecular Medical and Critical Area Pathology, University of Pisa, 56124 Pisa, Italy.
Gianluca Di BellaDepartment of Clinical and Experimental Medicine, University of Messina, 98100 Messina, Italy.
Michele MurziDivision of Adult Cardiac Surgery, Fondazione Toscana Gabriele Monasterio, 54100 Massa, Italy.
Silvia Di SibioDivision of Adult Cardiac Surgery, Fondazione Toscana Gabriele Monasterio, 54100 Massa, Italy.
Giovanni ConcistrèDivision of Adult Cardiac Surgery, Fondazione Toscana Gabriele Monasterio, 54100 Massa, Italy.ORCID 0000-0003-0395-8874
Giacomo BianchiDivision of Adult Cardiac Surgery, Fondazione Toscana Gabriele Monasterio, 54100 Massa, Italy.ORCID 0000-0003-4240-0099
Marco SolinasDivision of Adult Cardiac Surgery, Fondazione Toscana Gabriele Monasterio, 54100 Massa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfective endocarditis (IE) is marked by a heightened risk of embolic events (EEs), uncontrolled infection, or heart failure (HF).

methodsPatients with IE and surgical indication were enrolled from October 2015 to December 2018. The primary endpoint consisted of a composite of major adverse events (MAEs) including all-cause death, hospitalizations, and IE relapses. The secondary endpoint was all-cause death.

resultsA total of 102 patients (66 ± 14 years) were enrolled: 50% with IE on prosthesis, 33% with IE-associated heart failure (IE-aHF), and 38.2% with EEs. IE-aHF and EEs were independently associated with MAEs (HR 1.9, 95% CI 1.1-3.4,

conclusionsIE-aHF and EEs were independently associated with MAEs. IE-aHF was also independently associated with the secondary endpoint.

Indexed as

cardiac surgeryembolic eventsheart failureinfective endocarditis

Identifiers

PMID38786960
PMCPMC11121817

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.