Sulfonated Azocalix[4]arene-Modified Metal-Organic Framework Nanosheets for Doxorubicin Removal from Serum.

Xiao-Min Cao, Yuan-Qiu Cheng, Meng-Meng Chen, Shun-Yu Yao, An-Kang Ying, Xiu-Zhen Wang, Dong-Sheng Guo, Yue Li

Abstract read

In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiao-Min CaoCollege of Chemistry, Nankai University, Tianjin 300071, China.

Yuan-Qiu ChengCollege of Chemistry, Nankai University, Tianjin 300071, China.

Meng-Meng ChenCollege of Chemistry, Nankai University, Tianjin 300071, China.

Shun-Yu YaoCollege of Chemistry, Nankai University, Tianjin 300071, China.

An-Kang YingCollege of Chemistry, Nankai University, Tianjin 300071, China.

Xiu-Zhen WangCollege of Chemistry, Nankai University, Tianjin 300071, China.

Dong-Sheng GuoCollege of Chemistry, Nankai University, Tianjin 300071, China.

Yue LiCollege of Chemistry, Nankai University, Tianjin 300071, China.

Funding

National Natural Science Foundation of China 22376104National Natural Science Foundation of China U20A20259

6 · The paper itself

Abstract

Chemotherapy is one of the most commonly used methods for treating cancer, but its side effects severely limit its application and impair treatment effectiveness. Removing off-target chemotherapy drugs from the serum promptly through adsorption is the most direct approach to minimize their side effects. In this study, we synthesized a series of adsorption materials to remove the chemotherapy drug doxorubicin by modifying MOF nanosheets with sulfonated azocalix[4]arenes. The strong affinity of sulfonated azocalix[4]arenes for doxorubicin results in high adsorption strength (Langmuir adsorption constant = 2.45-5.73 L mg

Indexed as

adsorptiondoxorubicinmetal–organic frameworknanosheetsulfonated azocalix[4]arene

Identifiers

PMID38786820

DOI10.3390/nano14100864

PMCPMC11124067

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.