Evidence map›Paper›PMID 38786758›Full record

ArticleMetabolites2024

Volatile Organic Compounds in Cellular Headspace after Hyperbaric Oxygen Exposure: An In Vitro Pilot Study.

Feiko J M de Jong, Thijs A Lilien, Dominic W Fenn, Thijs T Wingelaar, Pieter-Jan A M van Ooij, Anke H Maitland-van der Zee, Markus W Hollmann, Rob A van Hulst, Paul Brinkman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Feiko J M de JongRoyal Netherlands Navy Diving and Submarine Medical Centre, 1780 CA Den Helder, The Netherlands.ORCID 0009-0008-9804-8307
Thijs A LilienDepartment of Pediatric Intensive Care, Amsterdam UMC, Location Emma Children's Hospital, 1100 DD Amsterdam, The Netherlands.
Dominic W FennDepartment of Pulmonology, Amsterdam UMC, Location AMC, 1100 DD Amsterdam, The Netherlands.ORCID 0000-0001-7904-8135
Thijs T WingelaarRoyal Netherlands Navy Diving and Submarine Medical Centre, 1780 CA Den Helder, The Netherlands.ORCID 0000-0001-7740-7392
Pieter-Jan A M van OoijRoyal Netherlands Navy Diving and Submarine Medical Centre, 1780 CA Den Helder, The Netherlands.ORCID 0000-0002-2108-320X
Anke H Maitland-van der ZeeDepartment of Pulmonology, Amsterdam UMC, Location AMC, 1100 DD Amsterdam, The Netherlands.ORCID 0000-0002-0414-3442
Markus W HollmannDepartment of Anesthesiology, Amsterdam UMC, Location AMC, 1100 DD Amsterdam, The Netherlands.ORCID 0000-0001-8248-0244
Rob A van HulstDepartment of Anesthesiology, Amsterdam UMC, Location AMC, 1100 DD Amsterdam, The Netherlands.
Paul BrinkmanDepartment of Pulmonology, Amsterdam UMC, Location AMC, 1100 DD Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Volatile organic compounds (VOCs) might be associated with pulmonary oxygen toxicity (POT). This pilot study aims to identify VOCs linked to oxidative stress employing an in vitro model of alveolar basal epithelial cells exposed to hyperbaric and hyperoxic conditions. In addition, the feasibility of this in vitro model for POT biomarker research was evaluated. The hyperbaric exposure protocol, similar to the U.S. Navy Treatment Table 6, was conducted on human alveolar basal epithelial cells, and the headspace VOCs were analyzed using gas chromatography-mass spectrometry. Three compounds (nonane [

Indexed as

GC-MSoxidative stresspulmonary oxygen toxicityTreatment Table 6

Identifiers

PMID38786758
PMCPMC11123173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.