Evidence map›Paper›PMID 38786334›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Predicting Response to Exclusive Combined Radio-Chemotherapy in Naso-Oropharyngeal Cancer: The Role of Texture Analysis.

Eleonora Bicci, Leonardo Calamandrei, Antonio Di Finizio, Michele Pietragalla, Sebastiano Paolucci, Simone Busoni, Francesco Mungai, Cosimo Nardi, Luigi Bonasera, Vittorio Miele

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eleonora BicciDepartment of Radiology, Azienda Ospedaliero-Universitaria Careggi, 50134 Florence, Italy.ORCID 0000-0002-1231-6200
Leonardo CalamandreiDepartment of Experimental and Clinical Biomedical Sciences, Radiodiagnostic Unit n. 2, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 3, 50134 Florence, Italy.ORCID 0000-0002-7681-7012
Antonio Di FinizioDepartment of Experimental and Clinical Biomedical Sciences, Radiodiagnostic Unit n. 2, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 3, 50134 Florence, Italy.ORCID 0009-0000-6515-9125
Michele PietragallaDepartment of Radiology, Ospedale San Jacopo, Via Ciliegiole 97, 51100 Pistoia, Italy.ORCID 0000-0003-4589-7109
Sebastiano PaolucciDepartment of Health Physics, L.Go Brambilla, Careggi University Hospital, 50134 Florence, Italy.
Simone BusoniDepartment of Health Physics, L.Go Brambilla, Careggi University Hospital, 50134 Florence, Italy.ORCID 0000-0001-7453-007X
Francesco MungaiDepartment of Radiology, Azienda Ospedaliero-Universitaria Careggi, 50134 Florence, Italy.ORCID 0000-0002-5212-2136
Cosimo NardiDepartment of Experimental and Clinical Biomedical Sciences, Radiodiagnostic Unit n. 2, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 3, 50134 Florence, Italy.ORCID 0000-0002-5489-7824
Luigi BonaseraDepartment of Radiology, Azienda Ospedaliero-Universitaria Careggi, 50134 Florence, Italy.
Vittorio MieleDepartment of Radiology, Azienda Ospedaliero-Universitaria Careggi, 50134 Florence, Italy.ORCID 0000-0002-7848-1567

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this work is to identify MRI texture features able to predict the response to radio-chemotherapy (RT-CHT) in patients with naso-oropharyngeal carcinoma (NPC-OPC) before treatment in order to help clinical decision making. Textural features were derived from ADC maps and post-gadolinium T1-images on a single MRI machine for 37 patients with NPC-OPC. Patients were divided into two groups (responders/non-responders) according to results from MRI scans and 18F-FDG-PET/CT performed at follow-up 3-4 and 12 months after therapy and biopsy. Pre-RT-CHT lesions were segmented, and radiomic features were extracted. A non-parametric Mann-Whitney test was performed. A

Indexed as

EBVhead and neckHPVmagnetic resonance imagingnaso-oropharyngeal tumorstexture analysis

Identifiers

PMID38786334
PMCPMC11120575

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.