Evidence map›Paper›PMID 38786276›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Two for One-Combined Morphologic and Quantitative Knee Joint MRI Using a Versatile Turbo Spin-Echo Platform.

Teresa Lemainque, Nicola Pridöhl, Marc Huppertz, Manuel Post, Can Yüksel, Robert Siepmann, Karl Ludger Radke, Shuo Zhang, Masami Yoneyama, Andreas Prescher and 3 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Teresa LemainqueDepartment of Diagnostic and Interventional Radiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0000-0003-3167-7121
Nicola PridöhlDepartment of Diagnostic and Interventional Radiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.
Marc HuppertzDepartment of Diagnostic and Interventional Radiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.
Manuel PostDepartment of Diagnostic and Interventional Radiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0000-0003-2810-6432
Can YükselDepartment of Diagnostic and Interventional Radiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0000-0002-1719-9875
Robert SiepmannDepartment of Diagnostic and Interventional Radiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.
Karl Ludger RadkeDepartment of Diagnostic and Interventional Radiology, University Hospital Düsseldorf, University Dusseldorf, 40225 Düsseldorf, Germany.ORCID 0000-0003-1095-1283
Shuo ZhangPhilips GmbH Market DACH, 22335 Hamburg, Germany.ORCID 0000-0002-1057-7255
Masami YoneyamaPhilips Japan, Tokyo 108-8507, Japan.ORCID 0000-0003-3517-2120
Andreas PrescherInstitute of Molecular and Cellular Anatomy, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.
Christiane KuhlDepartment of Diagnostic and Interventional Radiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.
Daniel TruhnDepartment of Diagnostic and Interventional Radiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0000-0002-9605-0728
Sven NebelungDepartment of Diagnostic and Interventional Radiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0000-0002-5267-9962

Funding

Deutsche Forschungsgemeinschaft NE 2136/3-1Deutsche Forschungsgemeinschaft (DFG) TR 1700/7-1European Union, Horizon Europe programme ODELIA, 01057091Faculty of Medicine, RWTH Aachen University, START programme 692316Federal Ministry of Education and Research SWAG, 01KD2215AFederal Ministry of Education and Research TRANSFORM LIVER, 031L0312A
6 · The paper itself

Abstract

Quantitative MRI techniques such as T2 and T1ρ mapping are beneficial in evaluating knee joint pathologies; however, long acquisition times limit their clinical adoption. MIXTURE (Multi-Interleaved X-prepared Turbo Spin-Echo with IntUitive RElaxometry) provides a versatile turbo spin-echo (TSE) platform for simultaneous morphologic and quantitative joint imaging. Two MIXTURE sequences were designed along clinical requirements: "MIX1", combining proton density (PD)-weighted fat-saturated (FS) images and T2 mapping (acquisition time: 4:59 min), and "MIX2", combining T1-weighted images and T1ρ mapping (6:38 min). MIXTURE sequences and their reference 2D and 3D TSE counterparts were acquired from ten human cadaveric knee joints at 3.0 T. Contrast, contrast-to-noise ratios, and coefficients of variation were comparatively evaluated using parametric tests. Clinical radiologists (

Indexed as

cartilageknee jointmagnetic resonance imagingquantitative imaging

Identifiers

PMID38786276
PMCPMC11120432

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.