Evidence map›Paper›PMID 38786114›Full record

ArticleAntibiotics (Basel, Switzerland)2024

Use of the Naturally Occurring Bacteriophage Grouping Model for the Design of Potent Therapeutic Cocktails.

Tea Glonti, Michael Goossens, Christel Cochez, Sabrina Green, Sayali Gorivale, Jeroen Wagemans, Rob Lavigne, Jean-Paul Pirnay

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tea GlontiLaboratory for Molecular and Cellular Technology, Queen Astrid Military Hospital, B-1120 Brussels, Belgium.ORCID 0000-0001-5814-3563
Michael GoossensLaboratory for Molecular and Cellular Technology, Queen Astrid Military Hospital, B-1120 Brussels, Belgium.
Christel CochezLaboratory for Molecular and Cellular Technology, Queen Astrid Military Hospital, B-1120 Brussels, Belgium.
Sabrina GreenLaboratory of Gene Technology, Department of Biosystems, KU Leuven, B-3001 Leuven, Belgium.
Sayali GorivaleLaboratory of Gene Technology, Department of Biosystems, KU Leuven, B-3001 Leuven, Belgium.
Jeroen WagemansLaboratory of Gene Technology, Department of Biosystems, KU Leuven, B-3001 Leuven, Belgium.ORCID 0000-0002-2185-5724
Rob LavigneLaboratory of Gene Technology, Department of Biosystems, KU Leuven, B-3001 Leuven, Belgium.ORCID 0000-0001-7377-1314
Jean-Paul PirnayLaboratory for Molecular and Cellular Technology, Queen Astrid Military Hospital, B-1120 Brussels, Belgium.ORCID 0000-0002-6863-5219

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The specificity of phages and their ability to evolve and overcome bacterial resistance make them potentially useful as adjuncts in the treatment of antibiotic-resistant bacterial infections. The goal of this study was to mimic a natural grouping of phages of interest and to evaluate the nature of their proliferation dynamics with bacteria. We have, for the first time, transferred naturally occurring phage groups directly from their sources of isolation to in vitro and identified 13

Indexed as

inhibition by phagephage antagonismphage Appelmans methodphage cocktailsphage isolationphage lytic activityphage proto-cooperationphage-resistant mutantsphage synergyphage web pattern method

Identifiers

PMID38786114
PMCPMC11117255

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.