Evidence map›Paper›PMID 38786094›Full record

ArticleCells2024

Melatonin Ameliorates Post-Stroke Cognitive Impairment in Mice by Inhibiting Excessive Mitophagy.

Yan Shi, Qian Fang, Yue Hu, Zhaoyu Mi, Shuting Luo, Yaoxue Gan, Shishan Yuan

Abstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yan ShiKey Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, School of Medicine, Hunan Normal University, Changsha 410006, China.
Qian FangDepartment of Medical Laboratory, School of Medicine, Hunan Normal University, Changsha 410006, China.
Yue HuDepartment of Medical Laboratory, School of Medicine, Hunan Normal University, Changsha 410006, China.
Zhaoyu MiDepartment of Medical Laboratory, School of Medicine, Hunan Normal University, Changsha 410006, China.
Shuting LuoKey Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, School of Medicine, Hunan Normal University, Changsha 410006, China.
Yaoxue GanDepartment of Medical Laboratory, School of Medicine, Hunan Normal University, Changsha 410006, China.
Shishan YuanKey Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, School of Medicine, Hunan Normal University, Changsha 410006, China.

Funding

Hunan Province Developmental Biology and Biological Breeding Key Programs 2022XKQ0205Hunan Provincial Natural Science Foundation of China 2021JJ40370Natural Science Foundation of China U22A20303Scientific Research Project of Hunan Provincial Health Commission 202102061699Scientific Research Project of Hunan Provincial Health Commission D202302089587
6 · The paper itself

Abstract

Post-stroke cognitive impairment (PSCI) remains the most common consequence of ischemic stroke. In this study, we aimed to investigate the role and mechanisms of melatonin (MT) in improving cognitive dysfunction in stroke mice. We used CoCl

Indexed as

Cognitive DysfunctionMelatoninMitophagyStrokeAnimalsApoptosisCell Line, TumorDisease Models, AnimalHumansMaleMiceMice, Inbred C57BLNeuronal PlasticityNeuronsProtein KinasesPTEN-Induced Putative KinaseMelatoninparkin proteinProtein KinasesPTEN-Induced Putative KinaseUbiquitin-Protein Ligasesmelatoninmitophagyneuroprotectivepost-stroke cognitive impairmentsynaptic plasticity

Identifiers

PMID38786094
PMCPMC11119717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.