Evidence map›Paper›PMID 38785741›Full record

ArticleDiseases (Basel, Switzerland)2024

Surgical Treatment of Lithiasis of the Main Pancreatic Duct: A Challenging Case and a Literature Review.

Dan Brebu, Cătălin Prodan-Bărbulescu, Vlad Braicu, Paul Pașca, George Borcean, Sabrina Florea, Clarisa Bîrlog, Amadeus Dobrescu, Mărioara Cornianu, Fulger Lazăr and 3 more

Abstract readCase Reports
In one paragraph

Article in Diseases (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Dan Brebu2nd Surgery Clinic, Timișoara Emergency County Hospital, 300723 Timisoara, Romania.
Cătălin Prodan-Bărbulescu2nd Surgery Clinic, Timișoara Emergency County Hospital, 300723 Timisoara, Romania.ORCID 0000-0003-4348-5469
Vlad Braicu2nd Surgery Clinic, Timișoara Emergency County Hospital, 300723 Timisoara, Romania.
Paul Pașca2nd Surgery Clinic, Timișoara Emergency County Hospital, 300723 Timisoara, Romania.
George Borcean2nd Surgery Clinic, Timișoara Emergency County Hospital, 300723 Timisoara, Romania.
Sabrina FloreaDepartment of Medical-Clinical Disciplines, Faculty of Medicine, "Titu Maiorescu" University of Bucharest, 031593 Bucharest, Romania.
Clarisa BîrlogDepartment of Surgery, Ponderas Academic Hospital, 021188 Bucharest, Romania.
Amadeus Dobrescu2nd Surgery Clinic, Timișoara Emergency County Hospital, 300723 Timisoara, Romania.ORCID 0000-0001-5736-572X
Mărioara CornianuDepartment of Microscopic Morphology-Morphopatology, ANAPATMOL Research Center, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Fulger Lazăr2nd Surgery Clinic, Timișoara Emergency County Hospital, 300723 Timisoara, Romania.
Bogdan Totolici1st Clinic of General Surgery, Arad County Emergency Clinical Hospital, 310158 Arad, Romania.
Ciprian Duță2nd Surgery Clinic, Timișoara Emergency County Hospital, 300723 Timisoara, Romania.
Flaviu Ionuț Faur2nd Surgery Clinic, Timișoara Emergency County Hospital, 300723 Timisoara, Romania.ORCID 0000-0001-6451-7461

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreaticolithiasis represents a rare phenomenon, being superimposed most of the time on a form of chronic pancreatitis of multifactorial etiology. Pancreaticolithiasis is a late complication of the phenomenon of chronic pancreatitis. The reverberant inflammatory process, followed by the fibrotic degeneration of the pancreatic parenchyma, and pancreatic fluid stasis at the ductal level are factors that contribute to the phenomenon of calcium precipitation. This article describes the case of a patient with a diagnosis of pancreaticolithiasis (Wirsung duct lithiasis), a phenomenon superimposed on chronic pancreatitis of ethanolic cause (Rosemont classification). It was decided to perform surgery via the classical approach with the perfection of corporeo-caudal pancreatectomy and preservation of the splenic vessels (Kimura procedure) with pancreatico-jejunal anastomosis on the Roux-en-Y loop. The aim of this study is to identify the best method of treatment for pancreaticolithiasis. To enhance the case and provide a basis for standardization, a literature review was carried out, which included a total of six articles. The results of this study highlight that, currently, the management of symptomatic pancreaticolithiasis encompasses medical therapy (enzyme replacement therapy), interventional therapy (ESWL (extracorporeal shock wave lithotripsy) ± ERCP (endoscopic retrograde cholangiopancreatography), ERCP + sphincterotomy + stent insertion, and POP (oral pancreatoscopy)), and surgical treatment. In conclusion, based on the analysis conducted in this study, the size of the calculi present determines which is the suitable therapeutic care. Unlike stones over 0.5 cm, when surgery is explicitly advised for therapeutic purposes in the absence of endoscopic techniques, stones under 0.5 cm should be treated using endoscopic procedures.

Indexed as

corporeo-caudal pancreatectomyKimura procedurelithiasis of main pancreatic ductpancreas duct stonepancreatic calculipancreaticolithiasisWirsung lithiasis

Identifiers

PMID38785741
PMCPMC11119672

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.